| IPI00229250 - Mafa, PANCREATIC BETA-CELL SPECIFIC TRANSCRIPTIONAL ACTIVATOR. | |
|---|---|
| Uniprot Accession: Q8CF90 | |
| Uniprot ID: Q8CF90_MOUSE | |
| Mapping: Chr 15, 75574098 - 75575177 | |
| Entrez Gene: 378435 | |
| Entrez MapView: |
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| MGI: MGI:2673307 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_7386) |
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| Rat: RGD1562627_predicted, SIMILAR TO MAFA HOMOLOG. |
| Mouse: Mafa, PANCREATIC BETA-CELL SPECIFIC TRANSCRIPTIONAL ACTIVATOR. |
| Human: MAFA, V-MAF MUSCULOAPONEUROTIC FIBROSARCOMA ONCOGENE HOMOLOG A. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| nucleus | C | IDA | IDA IDA | |
| transcription activator activity | F | IDA | ||
| DNA binding | F | IDA IDA | ||
| transcription factor activity | F | TAS | ||
| protein heterodimerization activity | F | NAS | ||
| protein homodimerization activity | F | TAS | ||
| sequence-specific DNA binding | F | IEA | ||
| regulation of transcription, DNA-dependent | P | TAS | IDA | |
| positive regulation of transcription from RNA polymerase II promoter | P | IDA | ||
| response to glucose stimulus | P | IDA |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| endocrine/exocrine gland phenotype | MP | Un | ||
| homeostasis/metabolism phenotype | MP | Un | ||
| renal/urinary system phenotype | MP | Un | ||
| digestive/alimentary phenotype | MP | Un | ||
| growth/size phenotype | MP | Un |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Type II diabetes mellitus (04930) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Maturity onset diabetes of the young (04950) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |