| IPI00229456 - Nfatc2, ISOFORM C OF NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 2. | |
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| Uniprot Accession: Q60591-3 | |
| Uniprot ID: NFAC2_MOUSE | |
| Mapping: Chr 2, 168167615 - 168292860 | |
| Entrez Gene: 18019 | |
| Entrez MapView: |
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| MGI: MGI:102463 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_4086) |
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| Rat: Nfatc2_predicted, CALCINEURIN-DEPENDENT 2 ISOFORM B ISOFORM 1. |
| Mouse: Nfatc2, ISOFORM A OF NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 2. |
| Mouse: Nfatc2, DEPENDENT 2. |
| Mouse: Nfatc2, ISOFORM C OF NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 2. |
| Mouse: Nfatc2, DEPENDENT 2 ISOFORM B. |
| Mouse: Nfatc2, NFATC2 PROTEIN. |
| Mouse: Nfatc2, DEPENDENT 2. |
| Mouse: Nfatc2, DEPENDENT 2 ISOFORM A. |
| Rat: Nfatc2_predicted, CALCINEURIN-DEPENDENT 2 ISOFORM A ISOFORM 3. |
| Rat: Nfatc2_predicted, 67 KDA PROTEIN. |
| Rat: Nfatc2_predicted, CALCINEURIN-DEPENDENT 2 ISOFORM B ISOFORM 2. |
| Human: NFATC2, ISOFORM B OF NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 2. |
| Human: NFATC2, ISOFORM C OF NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 2. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cytoplasm | C | IDA IDA | ISS ISS | |
| nucleus | C | IDA | ISS IEA | |
| transcription factor activity | F | IDA | ISS IEA | |
| transcription activator activity | F | ISS | ISS | |
| protein binding | F | IPI | ISS | |
| DNA binding | F | IDA IDA | ISS | |
| positive regulation of transcription | P | ISS | ISS | |
| regulation of transcription | P | IEA | ||
| regulation of transcription, DNA-dependent | P | IMP IDA | ISS ISS IEA | |
| positive regulation of transcription from RNA polymerase II promoter | P | IDA | ||
| cytokine production | P | IDA | ISS | |
| transcription | P | IEA |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| craniofacial phenotype | MP | Un | ||
| behavior/neurological phenotype | MP | Un | ||
| immune system phenotype | MP | Un Un | ||
| embryogenesis phenotype | MP | Un | ||
| skeleton phenotype | MP | Un | ||
| muscle phenotype | MP | Un | ||
| nervous system phenotype | MP | Un | ||
| respiratory system phenotype | MP | Un | ||
| vision/eye phenotype | MP | Un | ||
| hematopoietic system phenotype | MP | Un Un | ||
| growth/size phenotype | MP | Un |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| calcineurin signaling pathway | W | ISS | ||
| nuclear factor of activated T-cells signaling pathway | W | ISS |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| T cell receptor signaling pathway (04660) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| B cell receptor signaling pathway (04662) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| MAPK signaling pathway (04010) | Present in KEGG pathway | Present in KEGG pathway | Not present in KEGG pathway |
| VEGF signaling pathway (04370) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Wnt signaling pathway (04310) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Axon guidance (04360) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Natural killer cell mediated cytotoxicity (04650) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |