IpiRecord: IPI00229705

IPI00229705 - Dpyd, DIHYDROPYRIMIDINE DEHYDROGENASE.
Uniprot Accession: Q8K150
Uniprot ID: Q8K150_MOUSE
Mapping: Chr 3, 118554180 - 119424922
Entrez Gene: 99586
Entrez MapView: Geneprod
MGI: MGI:2139667
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_2803)
Rat: Dpyd, DIHYDROPYRIMIDINE DEHYDROGENASE.
Mouse: Dpyd, DIHYDROPYRIMIDINE DEHYDROGENASE.
Human: DPYD, DIHYDROPYRIMIDINE DEHYDROGENASE [NADP+] PRECURSOR.
Human: DPYD, DPYD PROTEIN.

Annotations for Dpyd and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
soluble fractionCIDA 
cytoplasmCNAS ISS IEA 
membraneCIEA 
cytosolCIDA ISS IDA 
FAD bindingFIEA IEA 
iron-sulfur cluster bindingFIEA IEA 
metal ion bindingFIEA IEA IEA 
dihydroorotate oxidase activityFIEA IEA 
electron carrier activityFIEA RCA ISS IEA 
iron ion bindingFIEA IEA IEA 
NADP bindingFIDA 
dihydroorotate dehydrogenase activityFIEA IEA 
uracil bindingFIDA 
dihydropyrimidine dehydrogenase (NADP+) activityFNAS IDA IDA ISS ISS IEA IDA 
oxidoreductase activityFIEA 
4 iron, 4 sulfur cluster bindingFIEA IEA IEA 
metabolic processPIEA IEA 
response to nutrientPIDA 
pyrimidine base catabolic processPIDA TAS ISS IDA 
thymidine catabolic processPNAS ISS 
'de novo' pyrimidine base biosynthetic processPIEA IEA 
circadian rhythmPIDA 
response to glucocorticoid stimulusPIEP 
uracil metabolic processPIDA 
uracil catabolic processPNAS ISS 
response to drugPIDA 
electron transportPIEA RCA ISS IEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (0)

There are no Mammalian Phenotype Ontology annotations for this protein in the database

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Liver DiseasesDIEP

Pathway (3)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
pantothenate and CoA biosynthetic pathwayWIEA
beta-alanine metabolic pathwayWIEA
pyrimidine metabolic pathwayWIEA IDA

KEGG Pathway (3)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
beta-Alanine metabolism (00410)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Pyrimidine metabolism (00240)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Pantothenate and CoA biosynthesis (00770)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway