IpiRecord: IPI00266006

IPI00266006 - Cblb, ISOFORM 2 OF E3 UBIQUITIN-PROTEIN LIGASE CBL-B.
Uniprot Accession: Q3TTA7-2
Uniprot ID: CBLB_MOUSE
Mapping: Chr 16, 51952371 - 52127389
Entrez Gene: 208650
Entrez MapView: Geneprod
MGI: MGI:2146430
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_10493)
Rat: Cblb, E3 UBIQUITIN-PROTEIN LIGASE CBL-B.
Mouse: Cblb, ISOFORM 2 OF E3 UBIQUITIN-PROTEIN LIGASE CBL-B.
Mouse: Cblb, ISOFORM 1 OF E3 UBIQUITIN-PROTEIN LIGASE CBL-B.
Rat: Cblb, 92 KDA PROTEIN.
Human: CBLB, ISOFORM LONG OF E3 UBIQUITIN-PROTEIN LIGASE CBL-B.
Human: CBLB, ISOFORM TRUNCATED 1 OF E3 UBIQUITIN-PROTEIN LIGASE CBL-B.
Human: CBLB, ISOFORM TRUNCATED 2 OF E3 UBIQUITIN-PROTEIN LIGASE CBL-B.
Human: CBLB, PUTATIVE UNCHARACTERIZED PROTEIN DKFZP779A0729.
Human: CBLB, 5 KDA PROTEIN.
Human: CBLB, PUTATIVE UNCHARACTERIZED PROTEIN DKFZP686J10223.
Human: CBLB, 44 KDA PROTEIN.

Annotations for Cblb and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
nucleusCIEA IEA 
cytoplasmCIEA 
protein bindingFIEA ISS IEA 
ligase activityFIEA IEA 
metal ion bindingFIEA 
signal transducer activityFIEA IEA 
calcium ion bindingFIEA IEA IEA 
zinc ion bindingFIEA IEA ISS IEA 
ubiquitin cyclePIEA IEA 
intracellular signaling cascadePIMP ISS IEA 
cell surface receptor linked signal transductionPIEA IEA 
immune responsePIMP ISS IEA 
T cell activationPIMP ISS 
negative regulation of T cell receptor signaling pathwayPIMP ISS 
NLS-bearing substrate import into nucleusPISS 
signal transductionPIDA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (7)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
skin/coat/nails phenotypeMPUn
immune system phenotypeMPUn Un
cardiovascular system phenotypeMPUn
hematopoietic system phenotypeMPUn
growth/size phenotypeMPUn
life span-post-weaning/agingMPUn
liver/biliary system phenotypeMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (4)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
T cell receptor signaling pathway (04660)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Chronic myeloid leukemia (05220)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Jak-STAT signaling pathway (04630)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Insulin signaling pathway (04910)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway