| IPI00311383 - Adipoq, ADIPONECTIN PRECURSOR. | |
|---|---|
| Uniprot Accession: Q60994 | |
| Uniprot ID: ADIPO_MOUSE | |
| Mapping: Chr 16, 23061870 - 23073302 | |
| Entrez Gene: 11450 | |
| Entrez MapView: |
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| MGI: MGI:106675 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_10637) |
|---|
| Rat: Adipoq, 30 KDA ADIPOCYTE COMPLEMENT-RELATED PROTEIN. |
| Mouse: Adipoq, ADIPONECTIN PRECURSOR. |
| Mouse: Adipoq, ADIPONECTIN, C1Q AND COLLAGEN DOMAIN CONTAINING. |
| Human: ADIPOQ, ADIPONECTIN PRECURSOR. |
| Human: ADIPOQ, 8 KDA PROTEIN. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| extracellular space | C | IEA | IDA IDA IDA IDA IDA IDA IDA IDA | ISS IDA |
| endoplasmic reticulum | C | IEA | IDA | ISS |
| cytoplasm | C | IEA | IEA | IEA |
| extracellular region | C | NAS | ||
| hormone activity | F | IEA | TAS IDA | ISS |
| receptor binding | F | IDA IDA IDA | ISS | |
| molecular_function | F | ND | ||
| protein binding | F | IPI IPI | ISS | |
| generation of precursor metabolites and energy | P | TAS | ||
| protein homooligomerization | P | IEA | IDA IDA IDA IDA | ISS |
| negative regulation of hormone secretion | P | IDA | ||
| response to hypoxia | P | IEP | ||
| fatty acid oxidation | P | IDA | NAS ISS | |
| response to sucrose stimulus | P | IEP | ||
| response to glucocorticoid stimulus | P | IEP | ||
| positive regulation of glucose import | P | IEA | IDA | ISS |
| positive regulation of fatty acid metabolic process | P | IEA | IMP | ISS |
| positive regulation of signal transduction | P | IDA IDA | ISS | |
| response to nutrient | P | IEP | ||
| glucose metabolic process | P | IEA | IDA IDA IDA IMP IMP | ISS |
| negative regulation of gluconeogenesis | P | IEA | IDA | ISS |
| phosphate transport | P | IEA | IEA | IEA |
| response to ethanol | P | IEP | ||
| response to glucose stimulus | P | IEA | IDA IMP IMP | ISS |
| positive regulation of I-kappaB kinase/NF-kappaB cascade | P | IEA | IDA IDA | ISS |
| glucose homeostasis | P | IEA | IDA IDA IMP IMP | ISS |
| response to drug | P | IEP | ||
| fatty acid beta-oxidation | P | IEA | IMP | ISS |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| skin/coat/nails phenotype | MP | Un | ||
| adipose tissue phenotype | MP | Un | ||
| behavior/neurological phenotype | MP | Un | ||
| endocrine/exocrine gland phenotype | MP | Un | ||
| homeostasis/metabolism phenotype | MP | Un Un Un Un | ||
| muscle phenotype | MP | Un | ||
| respiratory system phenotype | MP | Un | ||
| cardiovascular system phenotype | MP | Un Un | ||
| reproductive system phenotype | MP | Un | ||
| growth/size phenotype | MP | Un | ||
| liver/biliary system phenotype | MP | Un | ||
| life span-post-weaning/aging | MP | Un |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Hyperthyroidism | D | IEP | ||
| Obesity | D | IEP | ||
| Sepsis | D | IEP | ||
| Metabolic Syndrome X | D | ISS | ||
| Diabetes Mellitus, Experimental | D | IEP | ||
| Insulin Resistance | D | IEP | ||
| Fatty Liver | D | IEP | ||
| Hyperinsulinemia | D | IEP |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| adiponectin signaling pathway | W | ISS |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| PPAR signaling pathway (03320) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Adipocytokine signaling pathway (04920) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Type II diabetes mellitus (04930) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |