IpiRecord: IPI00314270

IPI00314270 - C6, COMPLEMENT COMPONENT 6.
Uniprot Accession: Q9QXT7
Uniprot ID: Q9QXT7_MOUSE
Mapping: Chr 15, 4681660 - 4748442
Entrez Gene: 12274
Entrez MapView: Geneprod
MGI: MGI:88233
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_2181)
Rat: C6, COMPLEMENT COMPONENT C6 PRECURSOR.
Mouse: C6, COMPLEMENT COMPONENT 6.
Human: C6, COMPLEMENT COMPONENT C6 PRECURSOR.

Annotations for C6 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
extracellular spaceCNR RCA ISS IDA 
membraneCNR 
membrane attack complexCIEA IEA 
molecular_functionFND 
caspase activationPIMP 
positive regulation of apoptosisPIMP 
complement activation, classical pathwayPIEA TAS IEA 
complement activationPIEA 
induction of apoptosisPIMP 
cytolysisPIEA IEA 
innate immune responsePIEA IEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (2)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
homeostasis/metabolism phenotypeMPUn
decreased susceptibility to experimental autoimmune myasthenia gravisNIAGP

Disease (7)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Kidney Failure, ChronicDIAGP
SepsisDIAGP
GlomerulonephritisDIAGP
ProteinuriaDIED
Encephalomyelitis, Experimental AutoimmuneDIAGP
Liver Diseases, AlcoholicDIAGP
Myasthenia Gravis, Experimental AutoimmuneDIAGP

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Complement and coagulation cascades (04610)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway