IpiRecord: IPI00314662

IPI00314662 - Nfatc2, DEPENDENT 2 ISOFORM B.
Uniprot Accession: Q91Y65
Uniprot ID: Q91Y65_MOUSE
Mapping: Chr 2, 168167615 - 168292860
Entrez Gene: 18019
Entrez MapView: Geneprod
MGI: MGI:102463
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_4086)
Rat: Nfatc2_predicted, CALCINEURIN-DEPENDENT 2 ISOFORM B ISOFORM 1.
Mouse: Nfatc2, ISOFORM A OF NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 2.
Mouse: Nfatc2, DEPENDENT 2.
Mouse: Nfatc2, ISOFORM C OF NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 2.
Mouse: Nfatc2, DEPENDENT 2 ISOFORM B.
Mouse: Nfatc2, NFATC2 PROTEIN.
Mouse: Nfatc2, DEPENDENT 2.
Mouse: Nfatc2, DEPENDENT 2 ISOFORM A.
Rat: Nfatc2_predicted, CALCINEURIN-DEPENDENT 2 ISOFORM A ISOFORM 3.
Rat: Nfatc2_predicted, 67 KDA PROTEIN.
Rat: Nfatc2_predicted, CALCINEURIN-DEPENDENT 2 ISOFORM B ISOFORM 2.
Human: NFATC2, ISOFORM B OF NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 2.
Human: NFATC2, ISOFORM C OF NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 2.

Annotations for Nfatc2 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
cytoplasmCIDA IDA ISS ISS 
nucleusCIDA ISS IEA 
transcription factor activityFIDA ISS IEA 
transcription activator activityFISS ISS 
protein bindingFIPI ISS 
DNA bindingFIDA IDA ISS 
positive regulation of transcriptionPISS ISS 
regulation of transcriptionPIEA 
regulation of transcription, DNA-dependentPIMP IDA ISS ISS IEA 
positive regulation of transcription from RNA polymerase II promoterPIDA 
cytokine productionPIDA ISS 
transcriptionPIEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (11)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
craniofacial phenotypeMPUn
behavior/neurological phenotypeMPUn
immune system phenotypeMPUn Un
embryogenesis phenotypeMPUn
skeleton phenotypeMPUn
muscle phenotypeMPUn
nervous system phenotypeMPUn
respiratory system phenotypeMPUn
vision/eye phenotypeMPUn
hematopoietic system phenotypeMPUn Un
growth/size phenotypeMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (2)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
calcineurin signaling pathwayWISS
nuclear factor of activated T-cells signaling pathwayWISS

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
T cell receptor signaling pathway (04660)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
B cell receptor signaling pathway (04662)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
MAPK signaling pathway (04010)Present in KEGG pathway Present in KEGG pathwayNot present in KEGG pathway
VEGF signaling pathway (04370)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Wnt signaling pathway (04310)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Axon guidance (04360)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Natural killer cell mediated cytotoxicity (04650)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway