IpiRecord: IPI00315100

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
cytoplasm	C	IEA	IEA
plasma membrane	C		IDA	IEA ISS
membrane	C	IEA	IEA
cytoskeleton	C	IEA	IEA	IEA
nucleus	C		IDA	IEA ISS
intracellular	C	IEA	IEA	IEA
cytosol	C		IDA TAS	ISS
magnesium ion binding	F	IEA
protein binding	F	IPI	IPI	IEA ISS
GTP binding	F	IEA	IEA IEA	IEA TAS
signal transducer activity	F	IEP		ISS
GTPase activity	F	TAS	TAS IDA IDA IDA	NAS TAS ISS
nucleotide binding	F	IEA	IEA	IEA
cell differentiation	P		IDA	ISS
actin cytoskeleton organization and biogenesis	P	TAS	IDA	TAS ISS
cell morphogenesis	P		IGI
integrin-mediated signaling pathway	P		TAS	ISS
cell adhesion	P		IMP	ISS
small GTPase mediated signal transduction	P	IEA	IEA	IEA
stress fiber formation	P		IDA IDA	ISS
negative regulation of neuron apoptosis	P		IMP	ISS
cell-matrix adhesion	P		IDA	ISS
positive regulation of I-kappaB kinase/NF-kappaB cascade	P	IEP		ISS
striated muscle development	P		IDA	ISS
Rho protein signal transduction	P	TAS	TAS IEA	ISS
negative regulation of neuron differentiation	P			IMP
positive regulation of NF-kappaB import into nucleus	P	NAS

Cellular Component

Biological Process

Molecular Function

Phenotype (0)

There are no Mammalian Phenotype Ontology annotations for this protein in the database

Disease (2)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Colorectal Neoplasms	D			ISS
Neoplasm Metastasis	D			ISS

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
Rho/Rac/Cdc42 mediated signaling pathway	W			TAS

KEGG Pathway (9)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
T cell receptor signaling pathway (04660)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Pathogenic Escherichia coli infection - EHEC (05130)	Present in KEGG pathway	Not present in KEGG pathway	Not present in KEGG pathway
TGF-beta signaling pathway (04350)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Adherens junction (04520)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Pathogenic Escherichia coli infection - EPEC (05131)	Present in KEGG pathway	Not present in KEGG pathway	Not present in KEGG pathway
Leukocyte transendothelial migration (04670)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Tight junction (04530)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Wnt signaling pathway (04310)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Regulation of actin cytoskeleton (04810)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Axon guidance (04360)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Focal adhesion (04510)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway