IpiRecord: IPI00320847
| IPI00320847 - Hsd17b10, 3-HYDROXYACYL-COA DEHYDROGENASE TYPE-2. | |
|---|---|
| Uniprot Accession: O08756 | |
| Uniprot ID: HCD2_MOUSE | |
| Mapping: Chr X, 147342597 - 147345155 | |
| Entrez Gene: 15108 | |
| Entrez MapView: |
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| MGI: MGI:1333871 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_14769) |
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| Rat: Hadh2, 3-HYDROXYACYL-COA DEHYDROGENASE TYPE-2. |
| Mouse: Hsd17b10, 3-HYDROXYACYL-COA DEHYDROGENASE TYPE-2. |
| Mouse: Hsd17b10, HYDROXYACYL-COENZYME A DEHYDROGENASE TYPE II. |
| Mouse: Hsd17b10, HYDROXYACYL-COENZYME A DEHYDROGENASE TYPE II. |
| Human: HSD17B10, ISOFORM 1 OF 3-HYDROXYACYL-COA DEHYDROGENASE TYPE-2. |
| Human: HSD17B10, ISOFORM 2 OF 3-HYDROXYACYL-COA DEHYDROGENASE TYPE-2. |
| Human: HSD17B10, HYDROXYSTEROID (17-BETA) DEHYDROGENASE 10. |
Annotations for Hsd17b10 and orthologs
GO Annotation Table
Compiled GO Annotations (from IPI)
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| plasma membrane | C | ISS | ||
| cytoplasm | C | ISS | ||
| endoplasmic reticulum | C | IDA | ISS IEA | |
| mitochondrion | C | IDA | IDA ISS ISS | |
| mitochondrial inner membrane | C | IDA | ISS IEA | |
| 7-alpha-hydroxysteroid dehydrogenase activity | F | ISS | ||
| oxidoreductase activity | F | IEA | IEA IEA | IEA |
| 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity | F | IEA | IEA | |
| 3-hydroxyacyl-CoA dehydrogenase activity | F | IEA | IEA | |
| 3(or 17)beta-hydroxysteroid dehydrogenase activity | F | ISS | ||
| protein binding | F | ISS | ||
| steroid metabolic process | P | ISS | ||
| metabolic process | P | IEA | IEA | IEA |
| lipid metabolic process | P | ISS |
Cellular Component
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
Biological Process
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
Molecular Function
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
Phenotype (1)
Compiled Mammalian Phenotype Ontology Annotations (from IPI)
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| increased mitochondrial oxidation | N | IEA |
Disease (0)
There are no Disease Ontology annotations for this protein in the database
Pathway (6)
Compiled Pathway Ontology Annotations (from IPI)
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| fatty acid metabolic pathway | W | IEA | ||
| valine, leucine and isoleucine degradation pathway | W | IEA | ||
| butanoate metabolic pathway | W | IEA | ||
| tryptophan metabolic pathway | W | IEA | ||
| benzoate degradation pathway via CoA ligation | W | IEA | ||
| lysine degradation pathway | W | IEA |
KEGG Pathway (7)
KEGG Pathways for this protein (from IPI)
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Caprolactam degradation (00930) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Alzheimer's disease (05010) | Present in KEGG pathway | Not present in KEGG pathway | Not present in KEGG pathway |
| Fatty acid metabolism (00071) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Lysine degradation (00310) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Tryptophan metabolism (00380) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Valine, leucine and isoleucine degradation (00280) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Butanoate metabolism (00650) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Fatty acid elongation in mitochondria (00062) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
© MCW Proteomics Center, 2006-2008
Supported by funds from the National Heart, Lung and Blood Institute