IpiRecord: IPI00322118

IPI00322118 - Vav1, PROTO-ONCOGENE VAV.
Uniprot Accession: Q3UAV5
Uniprot ID: Q3UAV5_MOUSE
Mapping: Chr 17, 56964450 - 57013288
Entrez Gene: 22324
Entrez MapView: Geneprod
MGI: MGI:98923
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_8544)
Rat: Vav1, PROTO-ONCOGENE VAV.
Mouse: Vav1, VAV-T.
Mouse: Vav1, PROTO-ONCOGENE VAV.
Mouse: Vav1, CLONE:F830016D21 PRODUCT:VAV 1 ONCOGENE, FULL INSERT SEQUENCE.
Mouse: Vav1, (FRAGMENT).
Mouse: Vav1, VAV1 PROTEIN.
Human: VAV1, PROTO-ONCOGENE VAV.
Human: VAV1, 20 KDA PROTEIN.
Human: VAV1, 6 KDA PROTEIN.
Human: VAV1, 9 KDA PROTEIN.

Annotations for Vav1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
endoplasmic reticulumCIEA 
nucleusCNR ISS 
intracellularCIEA IEA IEA IEA 
zinc ion bindingFIEA IEA IEA 
transcription factor activityFTAS ISS 
metal ion bindingFIEA IEA IEA 
protein bindingFIPI ISS 
Rho guanyl-nucleotide exchange factor activityFIGI IEA ISS 
diacylglycerol bindingFIEA IEA IEA 
guanyl-nucleotide exchange factor activityFIEA IEA IEA IEA TAS 
Rac guanyl-nucleotide exchange factor activityFIEA IGI ISS 
intracellular signaling cascadePIEA IMP IEA ISS 
regulation of progression through cell cyclePIEA 
regulation of Rho protein signal transductionPIEA IEA IEA 
immune responsePIEA IMP ISS 
cell developmentPTAS 
positive regulation of cell adhesionPIEA IGI ISS 
integrin-mediated signaling pathwayPIEA IGI ISS 
T cell differentiationPTAS ISS 
T cell activationPIMP ISS 
regulation of GTPase activityPIEA IGI ISS 
phagocytosisPIEA IGI ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (3)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
immune system phenotypeMPUn Un
normal phenotypeMPUn
hematopoietic system phenotypeMPUn Un

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
T cell receptor signaling pathway (04660)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
B cell receptor signaling pathway (04662)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Fc epsilon RI signaling pathway (04664)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Leukocyte transendothelial migration (04670)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Regulation of actin cytoskeleton (04810)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Natural killer cell mediated cytotoxicity (04650)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Focal adhesion (04510)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway