IpiRecord: IPI00323907

IPI00323907 - Csf2, GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR PRECURSOR.
Uniprot Accession: Q5SX78
Uniprot ID: Q5SX78_MOUSE
Mapping: Chr 11, 54090687 - 54093065
Entrez Gene: 12981
Entrez MapView: Geneprod
MGI: MGI:1339752
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_9339)
Rat: Csf2, SIMILAR TO GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR.
Mouse: Csf2, GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR PRECURSOR.
Human: CSF2, GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR PRECURSOR.

Annotations for Csf2 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
extracellular spaceCIEA RCA ISS IEA 
extracellular regionCIEA IEA IEA 
cytokine activityFIEA IDA IDA ISS IEA 
granulocyte macrophage colony-stimulating factor receptor bindingFTAS IEA IEA 
growth factor activityFIEA IEA 
cell surface receptor linked signal transductionPNR 
immune responsePIEA IEA IEA 
cellular defense responsePNR 
positive regulation of cell proliferationPIEA IDA IDA ISS IEA 
positive regulation of survival gene product activityPIEA IDA ISS IEA 
epithelial fluid transportPIDA 
positive regulation of macrophage differentiationPTAS 
epithelial cell proliferationPTAS 
myeloid dendritic cell differentiationPIEA IDA ISS IEA 
regulation of cell proliferationPIGI 
multicellular organismal developmentPNR 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (15)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
craniofacial phenotypeMPUn
endocrine/exocrine gland phenotypeMPUn
homeostasis/metabolism phenotypeMPUn
immune system phenotypeMPUn Un Un
embryogenesis phenotypeMPUn
lethality-embryonic/perinatalMPUn
skeleton phenotypeMPUn
lethality-postnatalMPUn Un
renal/urinary system phenotypeMPUn
respiratory system phenotypeMPUn Un Un
tumorigenesisMPUn
hematopoietic system phenotypeMPUn Un Un
reproductive system phenotypeMPUn
growth/size phenotypeMPUn
life span-post-weaning/agingMPUn Un Un

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (6)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
T cell receptor signaling pathway (04660)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Fc epsilon RI signaling pathway (04664)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Jak-STAT signaling pathway (04630)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Hematopoietic cell lineage (04640)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Cytokine-cytokine receptor interaction (04060)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Natural killer cell mediated cytotoxicity (04650)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway