IpiRecord: IPI00331664

IPI00331664 - Actn2, ALPHA-ACTININ-2.
Uniprot Accession: Q9JI91
Uniprot ID: ACTN2_MOUSE
Mapping: Chr 13, 12323759 - 12395065
Entrez Gene: 11472
Entrez MapView: Geneprod
MGI: MGI:109192
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_13290)
Rat: Actn2_predicted, SIMILAR TO ACTININ ALPHA 2.
Mouse: Actn2, ALPHA-ACTININ-2.
Mouse: Actn2, ACTININ ALPHA 2.
Mouse: Actn2, 18 KDA PROTEIN.
Human: ACTN2, ALPHA-ACTININ-2.

Annotations for Actn2 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
pseudopodiumCTAS ISS 
actin filamentCTAS ISS 
focal adhesionCIMP ISS 
Z discCIEA IDA ISS 
cytoskeletonCNAS ISS 
striated muscle thin filamentCTAS ISS 
cytoplasmCIEA IEA 
dendritic spineCTAS ISS 
filopodiumCIDA ISS 
identical protein bindingFIPI ISS 
actin bindingFIEA IEA IEA IEA 
protein bindingFIPI IPI ISS 
calcium ion bindingFIEA IEA IEA IEA 
thyroid hormone receptor coactivator activityFIEA IDA ISS 
protein binding, bridgingFTAS ISS 
integrin bindingFTAS ISS 
ligand-dependent nuclear receptor transcription coactivator activityFIDA ISS 
protein dimerization activityFIDA ISS 
actin filament bindingFTAS IDA ISS 
FATZ 1 bindingFIDA ISS 
structural constituent of muscleFTAS ISS 
ZASP bindingFIDA IDA IDA ISS 
protein homodimerization activityFTAS ISS 
focal adhesion formationPIMP ISS 
muscle contractionPIEA IPI ISS 
cell adhesionPTAS ISS 
microspike biogenesisPIDA ISS 
protein homotetramerizationPIDA ISS 
regulation of apoptosisPNAS ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (0)

There are no Mammalian Phenotype Ontology annotations for this protein in the database

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (5)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Adherens junction (04520)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Leukocyte transendothelial migration (04670)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Tight junction (04530)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Regulation of actin cytoskeleton (04810)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Focal adhesion (04510)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway