IpiRecord: IPI00352799

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
integral to plasma membrane	C			ISS ISS
Golgi apparatus	C		IDA	ISS ISS ISS
ciliary rootlet	C		IDA	ISS IEA
lysosomal membrane	C			IDA ISS
dendrite	C		IDA	ISS IEA
integral to nuclear inner membrane	C			ISS
endoplasmic reticulum	C		IDA	ISS ISS ISS
kinetochore	C			ISS
mitochondrial inner membrane	C			IDA
intracellular	C		IDA	ISS IEA
cytoplasmic vesicle	C		IDA	ISS IEA
mitochondrion	C			IDA ISS ISS
protein complex	C			IDA
nucleus	C		IDA	ISS IEA
membrane	C		IDA	ISS IEA
integral to membrane	C		RCA	ISS
cell soma	C		IDA	ISS IEA
neuromuscular junction	C			IDA
axon	C		IDA	ISS IEA
cell surface	C			IDA
membrane fraction	C		IDA	ISS ISS
hydrolase activity	F		IEA
endopeptidase activity	F		IMP ISS	IDA ISS IEA
protein binding	F		IPI IPI IPI IPI	IDA ISS ISS ISS
peptidase activity	F		IEA	IDA
anagen	P		IGI	ISS IEA
protein maturation via proteolysis	P		IMP IMP	ISS IEA
neuron migration	P		IMP IMP	ISS IEA
regulation of phosphorylation	P			ISS
membrane protein ectodomain proteolysis	P			ISS ISS
cellular calcium ion homeostasis	P		IMP	ISS IEA
embryonic limb morphogenesis	P		IGI	ISS IEA
chromosome segregation	P			ISS
chromosome organization and biogenesis (sensu Eukaryota)	P			ISS
apoptosis	P		IDA	ISS IEA
Notch receptor processing	P		IMP	ISS ISS
smooth endoplasmic reticulum calcium ion homeostasis	P		IGI	ISS IEA
intracellular signaling cascade	P		IEA	IEA
amyloid precursor protein catabolic process	P		IMP IMP	ISS ISS
eye photoreceptor cell development	P			NAS
positive regulation of enzyme activity	P			ISS ISS
negative regulation of neuron apoptosis	P			IMP
cell adhesion	P		IEA	IEA
protein maturation	P		IGI	ISS
cell fate specification	P		IGI	ISS IEA
positive regulation of apoptosis	P		IGI	ISS IEA
blood vessel development	P		IMP IMP	ISS IEA
heart development	P		IMP	ISS IEA
protein processing	P			IDA ISS ISS
memory	P		IMP	ISS IEA
anti-apoptosis	P			IDA ISS
brain development	P		IMP
somitogenesis	P		IMP
positive regulation of protein kinase activity	P		IDA	ISS IEA
Notch signaling pathway	P		IEA	IEA

Cellular Component

Biological Process

Molecular Function

Phenotype (29)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
cellular phenotype	MP		Un Un
skin/coat/nails phenotype	MP		Un Un Un Un
craniofacial phenotype	MP		Un Un Un
endocrine/exocrine gland phenotype	MP		Un
behavior/neurological phenotype	MP		Un Un Un Un Un Un
homeostasis/metabolism phenotype	MP		Un Un
growth/size phenotype	MP		Un Un Un Un Un Un Un
other phenotype	MP		Un Un Un
immune system phenotype	MP		Un
embryogenesis phenotype	MP		Un Un Un Un Un
lethality-embryonic/perinatal	MP		Un Un Un Un Un Un
lethality-postnatal	MP		Un
skeleton phenotype	MP		Un Un Un Un Un Un
life span-post-weaning/aging	MP		Un Un
hearing/vestibular/ear phenotype	MP		Un
nervous system phenotype	MP		Un Un Un Un Un Un Un Un Un Un Un
respiratory system phenotype	MP		Un
hematopoietic system phenotype	MP		Un
vision/eye phenotype	MP		Un
digestive/alimentary phenotype	MP		Un
normal phenotype	MP		Un Un Un
cardiovascular system phenotype	MP		Un Un Un Un Un Un
limbs/digits/tail phenotype	MP		Un Un Un Un Un Un
renal/urinary system phenotype	MP		Un
intracerebral hemorrhage	N			ISS
abnormal neuron morphology	N			ISS
increased apoptosis	N			IED
neonatal lethality	N			ISS
abnormal skeleton morphology	N			ISS

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Cerebral Hemorrhage	D			ISS

Pathway (2)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
Alzheimer disease pathway	W			IEA ISS
Notch signaling pathway	W			TAS

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Alzheimer's disease (05010)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Wnt signaling pathway (04310)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Notch signaling pathway (04330)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Neurodegenerative Disorders (01510)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway