IpiRecord: IPI00387295

IPI00387295 - Bace2, SEQUENCE.
Uniprot Accession: Q9R1P7
Uniprot ID: Q9R1P7_MOUSE
Mapping: Chr 16, 97461672 - 97543922
Entrez Gene: 56175
Entrez MapView: Geneprod
MGI: MGI:1860440
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_10436)
Rat: Bace2, BETA-SITE APP-CLEAVING ENZYME 2.
Mouse: Bace2, SEQUENCE.
Human: BACE2, BETA-SECRETASE 2 PRECURSOR.
Human: BACE2, BETA-SITE APP-CLEAVING ENZYME 2 ISOFORM C PREPROPROTEIN.
Human: BACE2, BETA-SITE APP-CLEAVING ENZYME 2 ISOFORM B PREPROPROTEIN.

Annotations for Bace2 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
extracellular spaceCRCA ISS 
membraneCIEA 
integral to membraneCNAS RCA ISS 
membrane fractionCTAS RCA ISS 
aspartic-type signal peptidase activityFIEA IEA 
pepsin A activityFIEA RCA ISS IEA 
aspartic-type endopeptidase activityFRCA ISS 
hydrolase activityFRCA ISS IEA 
peptidase activityFIEA IEA 
negative regulation of amyloid precursor protein biosynthetic processPIMP ISS ISS 
protein modification processPTAS RCA ISS 
membrane protein ectodomain proteolysisPIDA ISS ISS 
peptide hormone processingPNAS 
protein secretionPTAS RCA ISS 
proteolysisPRCA ISS IEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (4)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
cellular phenotypeMP#
lethality-postnatalMP#
nervous system phenotypeMP#
growth/size phenotypeMP#

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Alzheimer's disease (05010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway