IpiRecord: IPI00404981

IPI00404981 - Appbp1, NEDD8-ACTIVATING ENZYME E1 REGULATORY SUBUNIT.
Uniprot Accession: Q3UK27
Uniprot ID: Q3UK27_MOUSE
Mapping: Chr 8, 107400153 - 107423737
Entrez Gene: 234664
Entrez MapView: Geneprod
MGI: MGI:2384561
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_13788)
Rat: Appbp1, NEDD8-ACTIVATING ENZYME E1 REGULATORY SUBUNIT.
Mouse: Appbp1, NEDD8-ACTIVATING ENZYME E1 REGULATORY SUBUNIT.
Human: APPBP1, NEDD8-ACTIVATING ENZYME E1 REGULATORY SUBUNIT.
Human: APPBP1, UNCHARACTERIZED PROTEIN APPBP1.
Human: APPBP1, AMYLOID BETA PRECURSOR PROTEIN-BINDING PROTEIN 1 ISOFORM C.
Human: APPBP1, AMYLOID BETA PRECURSOR PROTEIN-BINDING PROTEIN 1 ISOFORM B.
Human: APPBP1, 61 KDA PROTEIN.

Annotations for Appbp1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
insoluble fractionCIDA ISS IEA 
cytoplasmCTAS ISS 
membraneCIEA IEA 
protein heterodimerization activityFIPI ISS ISS IEA 
catalytic activityFIEA RCA ISS IEA 
NEDD8 activating enzyme activityFIPI ISS ISS IEA 
protein bindingFIPI IPI IPI IPI ISS IEA 
apoptosisPIEA 
ubiquitin cyclePIEA IEA IEA 
protein neddylationPIDA IDA ISS ISS IEA 
DNA replicationPIDA ISS IEA 
S-M checkpointPIDA ISS IEA 
regulation of apoptosisPIDA IDA ISS IEA 
signal transductionPTAS ISS 
cell cyclePIEA IEA IEA 
induction of apoptosisPIDA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (0)

There are no Mammalian Phenotype Ontology annotations for this protein in the database

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (3)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
proteasome degradation pathway involving cullin-dependent ubiquitin ligasesWISS
Alzheimer disease pathwayWIEA
neddylation pathwayWISS

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Alzheimer's disease (05010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway