IpiRecord: IPI00407130
| IPI00407130 - Pkm2, ISOFORM M2 OF PYRUVATE KINASE ISOZYMES M1/M2. | |
|---|---|
| Uniprot Accession: P52480-1 | |
| Uniprot ID: KPYM_MOUSE | |
| Mapping: Chr 9, 59454614 - 59477381 | |
| Entrez Gene: 18746 | |
| Entrez MapView: |
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| MGI: MGI:97591 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_8097) |
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| Rat: Pkm2, ISOFORM M1 OF PYRUVATE KINASE ISOZYMES M1/M2. |
| Mouse: Pkm2, ISOFORM M2 OF PYRUVATE KINASE ISOZYMES M1/M2. |
| Mouse: Pkm2, ISOFORM M1 OF PYRUVATE KINASE ISOZYMES M1/M2. |
| Rat: Pkm2, ISOFORM M2 OF PYRUVATE KINASE ISOZYMES M1/M2. |
| Human: PKM2, ISOFORM M1 OF PYRUVATE KINASE ISOZYMES M1/M2. |
| Human: PKM2, ISOFORM M2 OF PYRUVATE KINASE ISOZYMES M1/M2. |
| Human: PKM2, PYRUVATE KINASE. |
| Human: PKM2, 30 KDA PROTEIN. |
| Human: PKM2, PYRUVATE KINASE. |
| Human: PKM2, 58 KDA PROTEIN. |
| Human: PKM2, 26 KDA PROTEIN. |
| Human: PKM2, 23 KDA PROTEIN. |
| Human: PKM2, 24 KDA PROTEIN. |
| Human: PKM2, 19 KDA PROTEIN. |
| Human: PKM2, 10 KDA PROTEIN. |
| Human: PKM2, PYRUVATE KINASE (FRAGMENT). |
Annotations for Pkm2 and orthologs
GO Annotation Table
Compiled GO Annotations (from IPI)
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cytosol | C | ISS | ||
| mitochondrion | C | IDA | ISS | |
| transferase activity | F | IEA | IEA | |
| protein binding | F | ISS | ||
| pyruvate kinase activity | F | IEA | IDA IDA | ISS ISS |
| potassium ion binding | F | IEA | ||
| catalytic activity | F | IEA | IEA | |
| kinase activity | F | IEA | ||
| magnesium ion binding | F | IEA | IEA | |
| metal ion binding | F | IEA | ||
| glycolysis | P | IEA | IEA | ISS |
Cellular Component
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
Biological Process
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
Molecular Function
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
Phenotype (0)
There are no Mammalian Phenotype Ontology annotations for this protein in the database
Disease (0)
There are no Disease Ontology annotations for this protein in the database
Pathway (4)
Compiled Pathway Ontology Annotations (from IPI)
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| glycolysis/gluconeogenesis pathway | W | IEA | ||
| pyruvate metabolic pathway | W | IEA | ||
| purine metabolic pathway | W | IEA | ||
| carbon fixation pathway | W | IEA |
KEGG Pathway (6)
KEGG Pathways for this protein (from IPI)
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Purine metabolism (00230) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Glycolysis / Gluconeogenesis (00010) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Type II diabetes mellitus (04930) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Carbon fixation (00710) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Pyruvate metabolism (00620) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Insulin signaling pathway (04910) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
© MCW Proteomics Center, 2006-2008
Supported by funds from the National Heart, Lung and Blood Institute