IpiRecord: IPI00407502
| IPI00407502 - C1r, COMPLEMENT C1R-A SUBCOMPONENT PRECURSOR. | |
|---|---|
| Uniprot Accession: Q8CG15 | |
| Uniprot ID: Q8CG15_MOUSE | |
| Mapping: Chr 6, 124478024 - 124546663 | |
| Entrez Gene: 50909 | |
| Entrez MapView: |
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| MGI: MGI:1355313 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_4869) |
|---|
| Rat: C1r, SIMILAR TO COMPLEMENT COMPONENT 1, R SUBCOMPONENT. |
| Mouse: C1r, COMPLEMENT C1R-A SUBCOMPONENT PRECURSOR. |
| Mouse: C1r, COMPLEMENT C1R-B SUBCOMPONENT PRECURSOR. |
| Mouse: C1r, 76 KDA PROTEIN. |
| Rat: C1r, 77 KDA PROTEIN. |
| Human: RP11-114H20.1, COMPLEMENT C1R SUBCOMPONENT PRECURSOR. |
| Human: C1R, UNCHARACTERIZED PROTEIN ENSP00000347341 (FRAGMENT). |
| Human: C1R, 26 KDA PROTEIN. |
| Mouse: Acyp1, FULL INSERT SEQUENCE. |
| Mouse: Acyp1, ACYLPHOSPHATASE-1. |
| Rat: Acyp1_predicted, 12 KDA PROTEIN. |
| Rat: Acyp1_predicted, SIMILAR TO ACYLPHOSPHATASE 1, ERYTHROCYTE (COMMON) TYPE. |
Annotations for C1r and orthologs
GO Annotation Table
Compiled GO Annotations (from IPI)
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cellular_component | C | ND | ||
| extracellular space | C | RCA | ||
| extracellular region | C | NAS | IEA | ISS |
| complement component C1s activity | F | IEA | ||
| trypsin activity | F | RCA | ||
| molecular_function | F | ND | ||
| peptidase activity | F | IEA | ||
| complement component C1r activity | F | TAS | IEA | ISS |
| hydrolase activity | F | IEA RCA | ISS | |
| catalytic activity | F | IEA | ||
| acylphosphatase activity | F | RCA | ISS ISS | |
| serine-type endopeptidase activity | F | IEA | IEA IEA | IEA |
| chymotrypsin activity | F | RCA | ||
| calcium ion binding | F | IEA | IEA | |
| complement activation | P | IEA | ||
| complement activation, classical pathway | P | IEA | IEA | |
| innate immune response | P | IEA | IEA | |
| immune response | P | IEA | ||
| phosphate metabolic process | P | ISS | ||
| proteolysis | P | IEA | RCA | IEA |
| biological_process | P | ND |
Cellular Component
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
Biological Process
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
Molecular Function
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
Phenotype (0)
There are no Mammalian Phenotype Ontology annotations for this protein in the database
Disease (1)
Compiled Disease Ontology Annotations (from IPI)
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Insulin Resistance | D | ISS |
Pathway (0)
There are no Pathway Ontology annotations for this protein in the database
KEGG Pathway (1)
KEGG Pathways for this protein (from IPI)
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Glycolysis / Gluconeogenesis (00010) | Not present in KEGG pathway | Present in KEGG pathway | Not present in KEGG pathway |
| Pyruvate metabolism (00620) | Not present in KEGG pathway | Present in KEGG pathway | Not present in KEGG pathway |
| Benzoate degradation via CoA ligation (00632) | Not present in KEGG pathway | Present in KEGG pathway | Not present in KEGG pathway |
| Complement and coagulation cascades (04610) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
© MCW Proteomics Center, 2006-2008
Supported by funds from the National Heart, Lung and Blood Institute