IPI report for IPI00407657

IpiRecord: IPI00407657

IPI00407657 - C8a, COMPLEMENT COMPONENT 8, ALPHA POLYPEPTIDE.
Uniprot Accession: Q8K1T7
Uniprot ID: Q8K1T7_MOUSE
Mapping: Chr 4, 104313604 - 104374315
Entrez Gene: 230558
Entrez MapView:
MGI: MGI:2668347
+All IPI Database Cross References Vega: OTTMUSP00000008476 UniProtKB/TrEMBL: A2A997 UniProtKB/TrEMBL: A2A997_MOUSE UniProtKB/TrEMBL: Q8BH67 UniProtKB/TrEMBL: Q8BH67_MOUSE UniProtKB/TrEMBL: Q8CHK0 UniProtKB/TrEMBL: Q8CHK0_MOUSE UniProtKB/TrEMBL: Q8K1T2 UniProtKB/TrEMBL: Q8K1T2_MOUSE UniProtKB/TrEMBL: Q8K1T7 UniProtKB/TrEMBL: Q8K1T7_MOUSE ENSEMBL: ENSMUSP00000067541 ENSEMBL: ENSMUSG00000035031 UniParc: UPI0000486313 MGI: MGI:2668347 Entrez Gene: 230558 UniGene: Mm.197638 trome: MTR001818 RZPD: Mm.197638 InterPro: IPR002172 InterPro: IPR001862 InterPro: IPR000884 Pfam: PF00057 Pfam: PF01823 PRINTS: PR00764 SMART: SM00192 SMART: SM00457 SMART: SM00209 PROSITE: PS01209 PROSITE: PS50068 PROSITE: PS00279 PROSITE: PS50092

IPI00407657 - C8a, COMPLEMENT COMPONENT 8, ALPHA POLYPEPTIDE.

Uniprot Accession: Q8K1T7

Uniprot ID: Q8K1T7_MOUSE

Mapping: Chr 4, 104313604 - 104374315

Entrez Gene: 230558

Entrez MapView: Geneprod

MGI: MGI:2668347

+All IPI Database Cross References

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_5544)
Rat: C8a_predicted, SIMILAR TO COMPLEMENT COMPONENT 8, ALPHA POLYPEPTIDE.
Mouse: C8a, COMPLEMENT COMPONENT 8, ALPHA POLYPEPTIDE.
Mouse: C8a, COMPLEMENT COMPONENT C8 ALPHA CHAIN PRECURSOR.
Mouse: C8a, COMPLEMENT COMPONENT 8 ALPHA SUBUNIT (FRAGMENT).
Mouse: C8a, COMPLEMENT COMPONENT 8, ALPHA POLYPEPTIDE.
Rat: C8a_predicted, 6 KDA PROTEIN.
Human: C8A, COMPLEMENT COMPONENT C8 ALPHA CHAIN PRECURSOR.
Human: C8A, 65 KDA PROTEIN.

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_5544)

Rat: C8a_predicted, SIMILAR TO COMPLEMENT COMPONENT 8, ALPHA POLYPEPTIDE.

Mouse: C8a, COMPLEMENT COMPONENT 8, ALPHA POLYPEPTIDE.

Mouse: C8a, COMPLEMENT COMPONENT C8 ALPHA CHAIN PRECURSOR.

Mouse: C8a, COMPLEMENT COMPONENT 8 ALPHA SUBUNIT (FRAGMENT).

Mouse: C8a, COMPLEMENT COMPONENT 8, ALPHA POLYPEPTIDE.

Rat: C8a_predicted, 6 KDA PROTEIN.

Human: C8A, COMPLEMENT COMPONENT C8 ALPHA CHAIN PRECURSOR.

Human: C8A, 65 KDA PROTEIN.

Annotations for C8a and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
extracellular space	C	TAS		ISS IDA
membrane	C	TAS		ISS
membrane attack complex	C	IDA	ISS	ISS
protein binding	F			IDA
protein complex binding	F			IDA
molecular_function	F		ND
innate immune response	P		IEA
complement activation, classical pathway	P	IEA	IEA
response to bacterium	P			ISS
complement activation, alternative pathway	P	IEA	IEA
immune response	P		IEA
cytolysis	P	IEA	IEA	IDA
complement activation	P		ISS

Cellular Component

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Phenotype (0)

There are no Mammalian Phenotype Ontology annotations for this protein in the database

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Myocardial Infarction	D			IEP

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Complement and coagulation cascades (04610)	Present in KEGG pathway	Present in KEGG pathway	Not present in KEGG pathway