IpiRecord: IPI00420718

IPI00420718 - Hmgcs2, HYDROXYMETHYLGLUTARYL-COA SYNTHASE, MITOCHONDRIAL PRECURSOR.
Uniprot Accession: Q8N7N8
Uniprot ID: Q8N7N8_MOUSE
Mapping: Chr 3, 98365840 - 98396137
Entrez Gene: 15360
Entrez MapView: Geneprod
MGI: MGI:101939
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_2569)
Rat: Hmgcs2, HYDROXYMETHYLGLUTARYL-COA SYNTHASE, MITOCHONDRIAL PRECURSOR.
Mouse: Hmgcs2, HYDROXYMETHYLGLUTARYL-COA SYNTHASE, MITOCHONDRIAL PRECURSOR.
Human: HMGCS2, HYDROXYMETHYLGLUTARYL-COA SYNTHASE, MITOCHONDRIAL PRECURSOR.

Annotations for Hmgcs2 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
mitochondrionCTAS IDA TAS ISS ISS IEA 
mitochondrial inner membraneCIEA IDA ISS IEA 
transferase activityFIEA IEA IEA 
hydroxymethylglutaryl-CoA synthase activityFIEA IEA IEA TAS IEA 
sterol biosynthetic processPIEA 
response to peptide hormone stimulusPIEP 
acetyl-CoA metabolic processPIEA IEA 
isoprenoid biosynthetic processPIEA 
response to nutrientPIEP 
cholesterol biosynthetic processPIEA IEA IEA 
ketone body biosynthetic processPTAS 
lipid biosynthetic processPIEA 
steroid biosynthetic processPIEA 
response to drugPIEP 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (0)

There are no Mammalian Phenotype Ontology annotations for this protein in the database

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (4)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
PPAR signaling pathway (03320)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Synthesis and degradation of ketone bodies (00072)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Valine, leucine and isoleucine degradation (00280)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Butanoate metabolism (00650)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway