IpiRecord: IPI00459269

IPI00459269 - Hmgcs1, SYNTHASE.
Uniprot Accession: Q8C5F4
Uniprot ID: Q8C5F4_MOUSE
Mapping: Chr , -
Entrez Gene: 208715
Entrez MapView: Geneprod
MGI: MGI:107592
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_2195)
Rat: Hmgcs1, HYDROXYMETHYLGLUTARYL-COA SYNTHASE, CYTOPLASMIC.
Mouse: Hmgcs1, HYDROXYMETHYLGLUTARYL-COA SYNTHASE, CYTOPLASMIC.
Mouse: Hmgcs1, SYNTHASE.
Human: HMGCS1, HYDROXYMETHYLGLUTARYL-COA SYNTHASE, CYTOPLASMIC.

Annotations for Hmgcs1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
cytosolCTAS 
cytoplasmCTAS IEA ISS 
soluble fractionCTAS ISS 
hydroxymethylglutaryl-CoA synthase activityFTAS RCA IEA TAS ISS ISS 
transferase activityFIEA IEA IEA 
lipid metabolic processPNAS ISS 
sterol biosynthetic processPIEA 
acetyl-CoA metabolic processPRCA IEA ISS 
cholesterol biosynthetic processPIEA IEA IEA 
lipid biosynthetic processPIEA 
steroid biosynthetic processPIEA 
isoprenoid biosynthetic processPIEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (0)

There are no Mammalian Phenotype Ontology annotations for this protein in the database

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (3)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
valine, leucine and isoleucine degradation pathwayWIEA
ketone bodies metabolic pathwayWIEA
butanoate metabolic pathwayWIEA

KEGG Pathway (3)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Synthesis and degradation of ketone bodies (00072)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Valine, leucine and isoleucine degradation (00280)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Butanoate metabolism (00650)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway