IpiRecord: IPI00473351

IPI00473351 - Als2, FULL INSERT SEQUENCE.
Uniprot Accession: Q9CX20
Uniprot ID: Q9CX20_MOUSE
Mapping: Chr 1, 59065489 - 59181765
Entrez Gene: 74018
Entrez MapView: Geneprod
MGI: MGI:1921268
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_15559)
Human: ALS2, ISOFORM 2 OF ALSIN.
Mouse: Als2, ISOFORM 2 OF ALSIN.
Mouse: Als2, ISOFORM 1 OF ALSIN.
Mouse: Als2, FULL INSERT SEQUENCE.
Mouse: Als2, 72 KDA PROTEIN.
Mouse: Als2, 55 KDA PROTEIN.
Human: ALS2, ISOFORM 1 OF ALSIN.
Human: ALS2, ISOFORM 3 OF ALSIN.

Annotations for Als2 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
cytoplasmCIDA 
nucleusCISS 
centrosomeCIDA ISS 
cytosolCISS 
dendritic spineCIDA 
postsynaptic densityCIDA 
early endosomeCISS 
intracellularCIEA 
guanyl-nucleotide exchange factor activityFIEA IEA 
Rab GTPase bindingFISS 
protein bindingFIPI ISS 
Rab GTPase activator activityFISS 
Rac GTPase activator activityFISS 
Rac GTPase bindingFISS 
identical protein bindingFISS 
Rho guanyl-nucleotide exchange factor activityFIEA 
vesicle organization and biogenesisPIDA 
response to oxidative stressPIMP 
behavioral fear responsePIMP 
receptor recyclingPIMP 
intracellular signaling cascadePIEA 
endosome organization and biogenesisPISS 
protein localizationPIMP 
regulation of Rho protein signal transductionPIEA 
synaptic transmission, glutamatergicPIMP 
locomotory behaviorPIMP IMP 
neuromuscular junction developmentPIMP 
regulation of Rab GTPase activityPIDA 
protein homooligomerizationPISS 
lysosomal transportPISS 
endosome transportPIMP IMP 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (7)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
behavior/neurological phenotypeMPUn Un Un
homeostasis/metabolism phenotypeMPUn
immune system phenotypeMPUn
muscle phenotypeMPUn
nervous system phenotypeMPUn Un Un
growth/size phenotypeMPUn
life span-post-weaning/agingMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Amyotrophic lateral sclerosis (ALS) (05030)Present in KEGG pathway Present in KEGG pathwayNot present in KEGG pathway
Neurodegenerative Disorders (01510)Present in KEGG pathway Present in KEGG pathwayNot present in KEGG pathway