IpiRecord: IPI00474191

IPI00474191 - Prkdc, DNA DEPENDENT PROTEIN KINASE, CATALYTIC SUBUNIT (FRAGMENT).
Uniprot Accession: Q91VE8
Uniprot ID: Q91VE8_MOUSE
Mapping: Chr 16, 15551467 - 15755813
Entrez Gene: 19090
Entrez MapView: Geneprod
MGI: MGI:104779
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_10693)
Rat: Prkdc_predicted, SIMILAR TO DNA-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT.
Mouse: Prkdc, ISOFORM 1 OF DNA-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT.
Mouse: Prkdc, DNA DEPENDENT PROTEIN KINASE, CATALYTIC SUBUNIT (FRAGMENT).
Mouse: Prkdc, ISOFORM 2 OF DNA-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT.
Rat: Prkdc_predicted, SIMILAR TO DNA-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT.
Human: PRKDC, ISOFORM 1 OF DNA-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT.
Human: PRKDC, ISOFORM 2 OF DNA-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT.

Annotations for Prkdc and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
cellular_componentCND 
nucleusCIDA ISS IEA 
protein bindingFISS 
bindingFIEA 
phosphotransferase activity, alcohol group as acceptorFIEA IEA 
transferase activityFIEA 
DNA bindingFIEA IEA 
protein serine/threonine kinase activityFIEA 
kinase activityFIEA 
ATP bindingFIEA IEA 
molecular_functionFND 
DNA-dependent protein kinase activityFIEA IEA 
telomere maintenancePIMP ISS 
pro-B cell differentiationPIMP 
immunoglobulin V(D)J recombinationPIMP 
T cell receptor V(D)J recombinationPIMP 
T cell differentiation in the thymusPIMP 
apoptosisPIMP ISS 
DNA repairPIEA 
protein modification processPISS 
response to gamma radiationPIMP 
double-strand break repairPIMP IMP ISS 
double-strand break repair via nonhomologous end joiningPIEA IEA 
response to DNA damage stimulusPIEA 
biological_processPND 
brain developmentPIGI ISS 
heart developmentPIGI ISS 
somitogenesisPIGI ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (6)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
cellular phenotypeMPUn Un
homeostasis/metabolism phenotypeMPUn
immune system phenotypeMPUn Un
tumorigenesisMPUn
hematopoietic system phenotypeMPUn Un
life span-post-weaning/agingMPUn

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Severe Combined ImmunodeficiencyDISS

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Cell cycle (04110)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway