| IPI00474564 - Abcc8, ATP-BINDING CASSETTE PROTEIN. | |
|---|---|
| Uniprot Accession: Q9JL44 | |
| Uniprot ID: Q9JL44_MOUSE | |
| Mapping: Chr 7, 45972565 - 46048075 | |
| Entrez Gene: 20927 | |
| Entrez MapView: |
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| MGI: MGI:1352629 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_571) |
|---|
| Rat: Abcc8, ISOFORM A OF ATP-BINDING CASSETTE TRANSPORTER SUB-FAMILY C MEMBER 8. |
| Mouse: Abcc8, ATP-BINDING CASSETTE PROTEIN. |
| Mouse: Abcc8, CLONE:D930031B21 PRODUCT:SULFONYLUREA RECEPTOR-1 HOMOLOG. |
| Mouse: Abcc8, ATP-BINDING CASSETTE, SUB-FAMILY C (CFTR/MRP), MEMBER 8. |
| Rat: Abcc8, 25 KDA PROTEIN. |
| Rat: Abcc8, 178 KDA PROTEIN. |
| Rat: Abcc8, 55 KDA PROTEIN. |
| Rat: Abcc8, ISOFORM B OF ATP-BINDING CASSETTE TRANSPORTER SUB-FAMILY C MEMBER 8. |
| Rat: Abcc8, ISOFORM C OF ATP-BINDING CASSETTE TRANSPORTER SUB-FAMILY C MEMBER 8. |
| Human: ABCC8, UNCHARACTERIZED PROTEIN ABCC8. |
| Human: ABCC8, ISOFORM 1 OF ATP-BINDING CASSETTE TRANSPORTER SUB-FAMILY C MEMBER 8. |
| Human: ABCC8, SULFONYLUREA RECEPTOR 1 VARIANT (FRAGMENT). |
| Human: ABCC8, 15 KDA PROTEIN. |
| Human: ABCC8, 19 KDA PROTEIN. |
| Human: ABCC8, 28 KDA PROTEIN. |
| Human: ABCC8, 18 KDA PROTEIN. |
| Human: ABCC8, 13 KDA PROTEIN. |
| Human: ABCC8, PROTEIN. |
| Human: ABCC8, 173 KDA PROTEIN. |
| Human: ABCC8, 10 KDA PROTEIN. |
| Human: ABCC8, 20 KDA PROTEIN. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| integral to membrane | C | IEA | IEA | |
| plasma membrane | C | IDA | ISS | |
| ATP-sensitive potassium channel complex | C | IMP TAS | ||
| membrane | C | IEA | RCA | IEA ISS |
| sarcolemma | C | IDA | ||
| synaptic vesicle membrane | C | IMP | ||
| ATP binding | F | IEA | IEA | IEA IMP ISS |
| syntaxin binding | F | IPI | ||
| receptor activity | F | IEA | IEA | IEA |
| sulfonylurea receptor activity | F | IEA | IEA TAS ISS | |
| potassium channel activity | F | IMP | ||
| ATPase activity, coupled to transmembrane movement of substances | F | IEA | IEA | |
| ATPase activity | F | IEA | IEA | |
| potassium ion transmembrane transporter activity | F | ISS | ||
| nucleotide binding | F | IEA | RCA | IEA ISS |
| potassium ion transport | P | IEA | IEA ISS | |
| negative regulation of insulin secretion | P | IDA | ||
| carbohydrate metabolic process | P | ISS | ||
| response to chemical stimulus | P | IDA | ||
| transport | P | IEA | IEA | |
| response to pH | P | IDA | ||
| positive regulation of potassium ion transport | P | IDA | ||
| response to zinc ion | P | IDA |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| endocrine/exocrine gland phenotype | MP | Un | ||
| homeostasis/metabolism phenotype | MP | Un Un | ||
| digestive/alimentary phenotype | MP | Un | ||
| increased circulating insulin level | N | IED |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Diabetes Mellitus | D | ISS | ||
| Diabetes Mellitus, Non-Insulin-Dependent | D | ISS | ||
| Hyperinsulinism | D | ISSISS | ||
| Cerebrovascular Accident | D | IED | ||
| Parkinsonian Disorders | D | IEP |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| ABC transporters - General (02010) | Present in KEGG pathway | Not present in KEGG pathway | Present in KEGG pathway |
| Type II diabetes mellitus (04930) | Present in KEGG pathway | Not present in KEGG pathway | Present in KEGG pathway |