IpiRecord: IPI00474888

IPI00474888 - Ptgis, CLONE:C130032H06 PRODUCT:PROSTAGLANDIN I2.
Uniprot Accession: Q8BXC0
Uniprot ID: Q8BXC0_MOUSE
Mapping: Chr 2, 166883022 - 166931749
Entrez Gene: 19223
Entrez MapView: Geneprod
MGI: MGI:1097156
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_4100)
Rat: Ptgis, PROSTACYCLIN SYNTHASE.
Mouse: Ptgis, PROSTACYCLIN SYNTHASE.
Mouse: Ptgis, CLONE:C130032H06 PRODUCT:PROSTAGLANDIN I2.
Rat: Ptgis, 24 KDA PROTEIN.
Human: PTGIS, PROSTACYCLIN SYNTHASE.

Annotations for Ptgis and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
endoplasmic reticulumCIEA IEA IEA 
extracellular spaceCRCA ISS IDA 
integral to membraneCIEA IEA IEA 
membraneCIEA IEA IEA 
monooxygenase activityFIEA RCA ISS IEA 
iron ion bindingFIEA IEA IEA IEA 
metal ion bindingFIEA IEA IEA 
isomerase activityFIEA IEA IEA 
prostaglandin-I synthase activityFTAS IEA IMP ISS IDA IEA 
heme bindingFIEA IEA IEA 
lipid metabolic processPNAS ISS 
lipid biosynthetic processPIEA 
response to hypoxiaPIMP 
prostaglandin biosynthetic processPIEA IEA TAS IDA IEA 
fatty acid biosynthetic processPIEA IEA IEA 
electron transportPIEA IEA IEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (3)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
homeostasis/metabolism phenotypeMPUn
renal/urinary system phenotypeMPUn
cardiovascular system phenotypeMPUn

Disease (3)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Hypertension, PulmonaryDIED
Brain IschemiaDIED
HypertensionDISS

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
eicosanoids metabolic pathwayWIEA

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Arachidonic acid metabolism (00590)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway