IpiRecord: IPI00553304

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
plasma membrane	C	NR
cytosol	C			IDA
cytoplasm	C	IEA	IEA
sarcolemma	C			ISS
hydrolase activity, hydrolyzing O-glycosyl compounds	F		RCA	ISS
arachidonate 15-lipoxygenase activity	F	IEA		IDA
lipoxygenase activity	F	TAS IEA	IEA	IEA
metal ion binding	F	IEA	IEA IEA	IEA
iron ion binding	F	IEA	IEA IEA	IEA
hepoxilin-epoxide hydrolase activity	F			IDA
oxidoreductase activity	F	IEA	IEA	IEA
arachidonate 12-lipoxygenase activity	F		IEA	IDA IEA
potassium channel inhibitor activity	F			TAS
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	F	IEA	IEA IEA
lipid metabolic process	P	NAS
arachidonic acid metabolic process	P			IDA NAS
fatty acid oxidation	P			ISS
negative regulation of cell volume	P			TAS
carbohydrate metabolic process	P		RCA	ISS
lipoxygenase pathway	P			IDA
inflammatory response	P	TAS
regulation of membrane potential	P			TAS
positive regulation of cell proliferation	P			ISS
leukotriene metabolic process	P	IEA	IEA
electron transport	P	IEA	IEA	IEA
leukotriene biosynthetic process	P	IEA	IEA	IEA
anti-apoptosis	P			ISS
positive regulation of cell growth	P			ISS

Cellular Component

Biological Process

Molecular Function

Phenotype (9)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
skin/coat/nails phenotype	MP		Un
endocrine/exocrine gland phenotype	MP		Un
immune system phenotype	MP		Un
life span-post-weaning/aging	MP		Un
hematopoietic system phenotype	MP		Un
reproductive system phenotype	MP		Un
tumorigenesis	MP		Un
abnormal apoptosis	N			IED
carcinoma	N			IED

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (2)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
lipoxygenase mediated pathway of arachidonic acid metabolism	W			IDA
eicosanoids metabolic pathway	W			IEA

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Arachidonic acid metabolism (00590)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Linoleic acid metabolism (00591)	Present in KEGG pathway	Not present in KEGG pathway	Not present in KEGG pathway