IpiRecord: IPI00556692

IPI00556692 - Smad2, ISOFORM LONG OF MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG 2.
Uniprot Accession: Q62432-1
Uniprot ID: SMAD2_MOUSE
Mapping: Chr 18, 76367274 - 76431096
Entrez Gene: 17126
Entrez MapView: Geneprod
MGI: MGI:108051
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_13772)
Rat: Smad2, MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG 2.
Mouse: Smad2, ISOFORM SHORT OF MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG 2.
Mouse: Smad2, ISOFORM LONG OF MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG 2.
Rat: Smad2, 49 KDA PROTEIN.
Human: SMAD2, ISOFORM LONG OF MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG 2.
Human: SMAD2, ISOFORM SHORT OF MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG 2.
Human: SMAD2, MEDULLOBLASTOMA ANTIGEN MU-MB-50.13.
Human: SMAD2, 8 KDA PROTEIN.
Human: SMAD2, 6 KDA PROTEIN.
Human: SMAD2, 20 KDA PROTEIN.
Human: SMAD2, 3 KDA PROTEIN.

Annotations for Smad2 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
cytoplasmCIEA IDA 
intracellularCIEA IEA IEA 
nucleusCIDA IDA IDA IDA IDA ISS ISS 
transcription factor complexCIEA IDA ISS ISS 
protein complexCIDA 
transcription factor activityFIEA 
transcription activator activityFIDA ISS ISS 
double-stranded DNA bindingFIDA ISS ISS 
protein bindingFIEA IPI IPI IPI ISS IPI 
transcription factor bindingFIPI ISS ISS 
transforming growth factor beta receptor signaling pathwayPIEA IDA IDA ISS ISS 
paraxial mesoderm morphogenesisPIMP ISS ISS 
intracellular signaling cascadePIDA ISS ISS 
mesoderm formationPIMP ISS ISS 
transcriptionPIEA IEA 
regulation of bindingPIDA ISS ISS 
cell fate commitmentPIMP ISS ISS 
positive regulation of transcription, DNA-dependentPIDA ISS 
positive regulation of transcription from RNA polymerase II promoterPIDA ISS ISS 
regulation of transcription, DNA-dependentPIEA IEA IEA 
SMAD protein complex assemblyPIEA 
common-partner SMAD protein phosphorylationPIEA 
anterior/posterior pattern formationPIMP ISS ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (17)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
craniofacial phenotypeMPUn Un
cellular phenotypeMPUn
homeostasis/metabolism phenotypeMPUn
immune system phenotypeMPUn
embryogenesis phenotypeMPUn Un Un Un Un Un
lethality-embryonic/perinatalMPUn Un Un Un Un Un Un
skeleton phenotypeMPUn Un
nervous system phenotypeMPUn
respiratory system phenotypeMPUn
vision/eye phenotypeMPUn
cardiovascular system phenotypeMPUn Un Un Un
digestive/alimentary phenotypeMPUn Un Un
normal phenotypeMPUn Un Un Un
growth/size phenotypeMPUn Un Un
no phenotypic analysisMPUn Un
life span-post-weaning/agingMPUn
liver/biliary system phenotypeMPUn

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Colorectal Neoplasms, Hereditary NonpolyposisDISS

Pathway (3)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
SMAD dependent signaling pathwaysWIDA
transforming growth factor-beta signaling pathway - SMAD dependentWIDA
activin signaling pathwayWTAS

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
TGF-beta signaling pathway (04350)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Cell cycle (04110)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Adherens junction (04520)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Wnt signaling pathway (04310)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Colorectal cancer (05210)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Pancreatic cancer (05212)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway