| IPI00556692 - Smad2, ISOFORM LONG OF MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG 2. | |
|---|---|
| Uniprot Accession: Q62432-1 | |
| Uniprot ID: SMAD2_MOUSE | |
| Mapping: Chr 18, 76367274 - 76431096 | |
| Entrez Gene: 17126 | |
| Entrez MapView: |
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| MGI: MGI:108051 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_13772) |
|---|
| Rat: Smad2, MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG 2. |
| Mouse: Smad2, ISOFORM SHORT OF MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG 2. |
| Mouse: Smad2, ISOFORM LONG OF MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG 2. |
| Rat: Smad2, 49 KDA PROTEIN. |
| Human: SMAD2, ISOFORM LONG OF MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG 2. |
| Human: SMAD2, ISOFORM SHORT OF MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG 2. |
| Human: SMAD2, MEDULLOBLASTOMA ANTIGEN MU-MB-50.13. |
| Human: SMAD2, 8 KDA PROTEIN. |
| Human: SMAD2, 6 KDA PROTEIN. |
| Human: SMAD2, 20 KDA PROTEIN. |
| Human: SMAD2, 3 KDA PROTEIN. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cytoplasm | C | IEA | IDA | |
| intracellular | C | IEA | IEA | IEA |
| nucleus | C | IDA IDA IDA IDA IDA | ISS ISS | |
| transcription factor complex | C | IEA | IDA | ISS ISS |
| protein complex | C | IDA | ||
| transcription factor activity | F | IEA | ||
| transcription activator activity | F | IDA | ISS ISS | |
| double-stranded DNA binding | F | IDA | ISS ISS | |
| protein binding | F | IEA | IPI IPI IPI | ISS IPI |
| transcription factor binding | F | IPI | ISS ISS | |
| transforming growth factor beta receptor signaling pathway | P | IEA | IDA IDA | ISS ISS |
| paraxial mesoderm morphogenesis | P | IMP | ISS ISS | |
| intracellular signaling cascade | P | IDA | ISS ISS | |
| mesoderm formation | P | IMP | ISS ISS | |
| transcription | P | IEA | IEA | |
| regulation of binding | P | IDA | ISS ISS | |
| cell fate commitment | P | IMP | ISS ISS | |
| positive regulation of transcription, DNA-dependent | P | IDA | ISS | |
| positive regulation of transcription from RNA polymerase II promoter | P | IDA | ISS ISS | |
| regulation of transcription, DNA-dependent | P | IEA | IEA IEA | |
| SMAD protein complex assembly | P | IEA | ||
| common-partner SMAD protein phosphorylation | P | IEA | ||
| anterior/posterior pattern formation | P | IMP | ISS ISS |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| craniofacial phenotype | MP | Un Un | ||
| cellular phenotype | MP | Un | ||
| homeostasis/metabolism phenotype | MP | Un | ||
| immune system phenotype | MP | Un | ||
| embryogenesis phenotype | MP | Un Un Un Un Un Un | ||
| lethality-embryonic/perinatal | MP | Un Un Un Un Un Un Un | ||
| skeleton phenotype | MP | Un Un | ||
| nervous system phenotype | MP | Un | ||
| respiratory system phenotype | MP | Un | ||
| vision/eye phenotype | MP | Un | ||
| cardiovascular system phenotype | MP | Un Un Un Un | ||
| digestive/alimentary phenotype | MP | Un Un Un | ||
| normal phenotype | MP | Un Un Un Un | ||
| growth/size phenotype | MP | Un Un Un | ||
| no phenotypic analysis | MP | Un Un | ||
| life span-post-weaning/aging | MP | Un | ||
| liver/biliary system phenotype | MP | Un |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Colorectal Neoplasms, Hereditary Nonpolyposis | D | ISS |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| SMAD dependent signaling pathways | W | IDA | ||
| transforming growth factor-beta signaling pathway - SMAD dependent | W | IDA | ||
| activin signaling pathway | W | TAS |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| TGF-beta signaling pathway (04350) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Cell cycle (04110) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Adherens junction (04520) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Wnt signaling pathway (04310) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Colorectal cancer (05210) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Pancreatic cancer (05212) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |