| IPI00556735 - Akt1, THYMOMA VIRAL PROTO-ONCOGENE 1. | |
|---|---|
| Uniprot Accession: Q8BS26 | |
| Uniprot ID: Q8BS26_MOUSE | |
| Mapping: Chr 12, 113101636 - 113122084 | |
| Entrez Gene: 100047666 | |
| Entrez MapView: |
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| MGI: MGI:87986 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_6527) |
|---|
| Rat: Akt1, RAC-ALPHA SERINE/THREONINE-PROTEIN KINASE. |
| Mouse: Akt1, RAC-ALPHA SERINE/THREONINE-PROTEIN KINASE. |
| Mouse: Akt1, THYMOMA VIRAL PROTO-ONCOGENE 1. |
| Human: AKT1, RAC-ALPHA SERINE/THREONINE-PROTEIN KINASE. |
| Human: AKT1, SERINE/THREONINE KINASE. |
| Human: AKT1, 2 KDA PROTEIN. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cytoplasm | C | ISS | IDA | IDA ISS IEA |
| plasma membrane | C | IDA | ISS | |
| lamellipodium | C | IEA | IDA | ISS IEA |
| spindle | C | IEA | IDA | ISS IEA |
| nucleus | C | IEA | IEA | IEA |
| identical protein binding | F | IPI | ISS IEA | |
| protein kinase activity | F | IEA | IDA IDA IDA | IDA ISS |
| receptor signaling protein serine/threonine kinase activity | F | ISS | ||
| kinase activity | F | ISS | ||
| transferase activity | F | IEA | IEA | IEA |
| ATP binding | F | IC IEA | IEA IEA | IEA |
| protein binding | F | IPI IPI IPI | IPI IDA ISS | |
| sugar:hydrogen ion symporter activity | F | IEA | IEA | IEA |
| protein-tyrosine kinase activity | F | ISS | ||
| protein serine/threonine kinase activity | F | IDA IDA | IEA IEA | TAS ISS |
| nucleotide binding | F | IEA | IEA | IEA |
| inflammatory response | P | IEA | IDA | ISS IEA |
| protein ubiquitination | P | IEA | IDA | ISS IEA |
| regulation of cell migration | P | IMP | ||
| carbohydrate metabolic process | P | IEA | IEA | IEA |
| negative regulation of apoptosis | P | IMP | ISS IEA | |
| intracellular signaling cascade | P | IDA | ISS | |
| protein catabolic process | P | IEA | IDA | ISS IEA |
| protein kinase B signaling cascade | P | IEA | IGI | |
| carbohydrate transport | P | IEA | IEA | |
| protein amino acid autophosphorylation | P | TAS | ||
| peptidyl-serine phosphorylation | P | IDA | ||
| anagen | P | IEA | IMP | ISS IEA |
| glucose transport | P | IEA | IMP | IEA |
| G-protein coupled receptor protein signaling pathway | P | TAS | ISS | |
| nitric oxide biosynthetic process | P | TAS | ISS | |
| glucose metabolic process | P | IEA | IEA | IEA |
| protein import into nucleus, translocation | P | IMP | IEA | |
| cell projection organization and biogenesis | P | ISS | ||
| insulin-like growth factor receptor signaling pathway | P | IMP | ISS ISS | |
| apoptosis | P | IDA | ISS IEA | |
| protein amino acid phosphorylation | P | IEA | ISS IDA IDA IDA | IDA ISS ISS ISS |
| blood vessel development | P | IEA | IMP | |
| protein modification process | P | TAS | ||
| glycogen metabolic process | P | IMP | ||
| placenta development | P | IEA | IMP | |
| activated T cell apoptosis | P | IMP | ISS | |
| germ cell development | P | IEA | IDA | ISS IEA |
| regulation of translation | P | IEA | IEA | IEA |
| negative regulation of cell size | P | ISS | ||
| anti-apoptosis | P | TAS IMP ISS | ||
| signal transduction | P | IDA ISS | ||
| positive regulation of body size | P | IEA | IMP | |
| transport | P | IEA | IEA | |
| insulin receptor signaling pathway | P | IMP | IMP IMP | ISS ISS IMP |
| response to heat | P | TAS | ISS | |
| positive regulation of cell growth | P | IDA | ||
| regulation of survival gene product activity | P | IEA | IDA | ISS IEA |
| response to hormone stimulus | P | IEA | IDA | IEA |
| glycogen biosynthetic process | P | IEA | IEA | IMP |
| apoptotic mitochondrial changes | P | IEA | IDA | ISS IEA |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| skin/coat/nails phenotype | MP | Un Un | ||
| endocrine/exocrine gland phenotype | MP | Un | ||
| homeostasis/metabolism phenotype | MP | Un | ||
| immune system phenotype | MP | Un | ||
| embryogenesis phenotype | MP | Un | ||
| lethality-embryonic/perinatal | MP | Un Un | ||
| skeleton phenotype | MP | Un | ||
| lethality-postnatal | MP | Un | ||
| muscle phenotype | MP | Un Un | ||
| liver/biliary system phenotype | MP | Un | ||
| respiratory system phenotype | MP | Un | ||
| growth/size phenotype | MP | Un Un Un | ||
| cardiovascular system phenotype | MP | Un | ||
| hematopoietic system phenotype | MP | Un | ||
| reproductive system phenotype | MP | Un | ||
| life span-post-weaning/aging | MP | Un | ||
| nervous system phenotype | MP | Un | ||
| testicular hypoplasia | N | ISS |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| phosphatidylinositol 3 kinase-Akt signaling pathway | W | IMP |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Glioma (05214) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| T cell receptor signaling pathway (04660) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Chronic myeloid leukemia (05220) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| B cell receptor signaling pathway (04662) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| mTOR signaling pathway (04150) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Toll-like receptor signaling pathway (04620) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Adipocytokine signaling pathway (04920) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Fc epsilon RI signaling pathway (04664) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Apoptosis (04210) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| MAPK signaling pathway (04010) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Jak-STAT signaling pathway (04630) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| VEGF signaling pathway (04370) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Tight junction (04530) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Colorectal cancer (05210) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Pancreatic cancer (05212) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Insulin signaling pathway (04910) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Focal adhesion (04510) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |