IpiRecord: IPI00556735

IPI00556735 - Akt1, THYMOMA VIRAL PROTO-ONCOGENE 1.
Uniprot Accession: Q8BS26
Uniprot ID: Q8BS26_MOUSE
Mapping: Chr 12, 113101636 - 113122084
Entrez Gene: 100047666
Entrez MapView: Geneprod
MGI: MGI:87986
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_6527)
Rat: Akt1, RAC-ALPHA SERINE/THREONINE-PROTEIN KINASE.
Mouse: Akt1, RAC-ALPHA SERINE/THREONINE-PROTEIN KINASE.
Mouse: Akt1, THYMOMA VIRAL PROTO-ONCOGENE 1.
Human: AKT1, RAC-ALPHA SERINE/THREONINE-PROTEIN KINASE.
Human: AKT1, SERINE/THREONINE KINASE.
Human: AKT1, 2 KDA PROTEIN.

Annotations for Akt1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
cytoplasmCISS IDA IDA ISS IEA 
plasma membraneCIDA ISS 
lamellipodiumCIEA IDA ISS IEA 
spindleCIEA IDA ISS IEA 
nucleusCIEA IEA IEA 
identical protein bindingFIPI ISS IEA 
protein kinase activityFIEA IDA IDA IDA IDA ISS 
receptor signaling protein serine/threonine kinase activityFISS 
kinase activityFISS 
transferase activityFIEA IEA IEA 
ATP bindingFIC IEA IEA IEA IEA 
protein bindingFIPI IPI IPI IPI IDA ISS 
sugar:hydrogen ion symporter activityFIEA IEA IEA 
protein-tyrosine kinase activityFISS 
protein serine/threonine kinase activityFIDA IDA IEA IEA TAS ISS 
nucleotide bindingFIEA IEA IEA 
inflammatory responsePIEA IDA ISS IEA 
protein ubiquitinationPIEA IDA ISS IEA 
regulation of cell migrationPIMP 
carbohydrate metabolic processPIEA IEA IEA 
negative regulation of apoptosisPIMP ISS IEA 
intracellular signaling cascadePIDA ISS 
protein catabolic processPIEA IDA ISS IEA 
protein kinase B signaling cascadePIEA IGI 
carbohydrate transportPIEA IEA 
protein amino acid autophosphorylationPTAS 
peptidyl-serine phosphorylationPIDA 
anagenPIEA IMP ISS IEA 
glucose transportPIEA IMP IEA 
G-protein coupled receptor protein signaling pathwayPTAS ISS 
nitric oxide biosynthetic processPTAS ISS 
glucose metabolic processPIEA IEA IEA 
protein import into nucleus, translocationPIMP IEA 
cell projection organization and biogenesisPISS 
insulin-like growth factor receptor signaling pathwayPIMP ISS ISS 
apoptosisPIDA ISS IEA 
protein amino acid phosphorylationPIEA ISS IDA IDA IDA IDA ISS ISS ISS 
blood vessel developmentPIEA IMP 
protein modification processPTAS 
glycogen metabolic processPIMP 
placenta developmentPIEA IMP 
activated T cell apoptosisPIMP ISS 
germ cell developmentPIEA IDA ISS IEA 
regulation of translationPIEA IEA IEA 
negative regulation of cell sizePISS 
anti-apoptosisPTAS IMP ISS 
signal transductionPIDA ISS 
positive regulation of body sizePIEA IMP 
transportPIEA IEA 
insulin receptor signaling pathwayPIMP IMP IMP ISS ISS IMP 
response to heatPTAS ISS 
positive regulation of cell growthPIDA 
regulation of survival gene product activityPIEA IDA ISS IEA 
response to hormone stimulusPIEA IDA IEA 
glycogen biosynthetic processPIEA IEA IMP 
apoptotic mitochondrial changesPIEA IDA ISS IEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (18)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
skin/coat/nails phenotypeMPUn Un
endocrine/exocrine gland phenotypeMPUn
homeostasis/metabolism phenotypeMPUn
immune system phenotypeMPUn
embryogenesis phenotypeMPUn
lethality-embryonic/perinatalMPUn Un
skeleton phenotypeMPUn
lethality-postnatalMPUn
muscle phenotypeMPUn Un
liver/biliary system phenotypeMPUn
respiratory system phenotypeMPUn
growth/size phenotypeMPUn Un Un
cardiovascular system phenotypeMPUn
hematopoietic system phenotypeMPUn
reproductive system phenotypeMPUn
life span-post-weaning/agingMPUn
nervous system phenotypeMPUn
testicular hypoplasiaNISS

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
phosphatidylinositol 3 kinase-Akt signaling pathwayWIMP

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Glioma (05214)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
T cell receptor signaling pathway (04660)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Chronic myeloid leukemia (05220)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
B cell receptor signaling pathway (04662)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
mTOR signaling pathway (04150)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Toll-like receptor signaling pathway (04620)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Adipocytokine signaling pathway (04920)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Fc epsilon RI signaling pathway (04664)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Apoptosis (04210)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
MAPK signaling pathway (04010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Jak-STAT signaling pathway (04630)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
VEGF signaling pathway (04370)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Tight junction (04530)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Colorectal cancer (05210)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Pancreatic cancer (05212)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Insulin signaling pathway (04910)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Focal adhesion (04510)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway