IpiRecord: IPI00620622

IPI00620622 - Src, ROUS SARCOMA ONCOGENE ISOFORM 2.
Uniprot Accession: Q80XU2
Uniprot ID: Q80XU2_MOUSE
Mapping: Chr 2, 157115730 - 157163279
Entrez Gene: 20779
Entrez MapView: Geneprod
MGI: MGI:98397
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_4144)
Rat: Src, NEURONAL C-SRC TYROSINE-SPECIFIC PROTEIN KINASE.
Mouse: Src, NEURONAL PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC.
Mouse: Src, ROUS SARCOMA ONCOGENE ISOFORM 2.
Mouse: Src, ROUS SARCOMA ONCOGENE ISOFORM 1.
Human: SRC, ISOFORM 2 OF PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC.
Human: SRC, ISOFORM 1 OF PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC.
Human: SRC, NORVEGICUS TYROSINE PROTEIN KINASE PP60-C-SRC MRNA.
Human: SRC, 60 KDA PROTEIN.

Annotations for Src and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
plasma membraneCIDA 
intracellularCIEA 
protein-tyrosine kinase activityFIEA IMP IDA ISS IEA 
ATP bindingFIEA IEA IEA IEA 
protein serine/threonine kinase activityFISS 
kinase activityFIMP TAS ISS 
protein C-terminus bindingFIPI 
protein kinase activityFIDA ISS 
protein bindingFIPI IPI ISS IDA IDA 
transferase activityFIEA IEA 
nucleotide bindingFIEA IEA 
intracellular signaling cascadePIEA IEA IEA 
regulation of progression through cell cyclePIEA 
positive regulation of insulin receptor signaling pathwayPIDA 
peptidyl-tyrosine phosphorylationPIDA ISS 
transcytosisPIDA 
cell proliferationPIDA 
protein amino acid phosphorylationPIEA IDA ISS IEA 
response to acidPIEP 
forebrain developmentPIGI ISS 
cell-cell adhesionPIEP 
epidermal growth factor receptor signaling pathwayPIEP 
response to stressPIDA 
platelet-derived growth factor receptor signaling pathwayPIEP 
nerve growth factor receptor signaling pathwayPIDA 
response to mineralocorticoid stimulusPIDA 
positive regulation of apoptosisPIDA 
positive regulation of cell adhesionPIDA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (12)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
craniofacial phenotypeMPUn
behavior/neurological phenotypeMPUn
immune system phenotypeMPUn
lethality-embryonic/perinatalMPUn
skeleton phenotypeMPUn
lethality-postnatalMPUn
respiratory system phenotypeMPUn
limbs/digits/tail phenotypeMPUn
hematopoietic system phenotypeMPUn
reproductive system phenotypeMPUn
growth/size phenotypeMPUn
life span-post-weaning/agingMPUn

Disease (7)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Diabetes Mellitus, Non-Insulin-DependentDISS
Status EpilepticusDIED
Brain IschemiaDIED
Colonic NeoplasmsDISS
Neoplasm MetastasisDISS
HypertensionDIED
Parkinsonian DisordersDIED

Pathway (7)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
nerve growth factor signaling pathwayWIDA
somatostatin signaling pathwayWIDA
dopamine signaling pathwayWIDA
platelet-derived growth factor signaling pathwayWIEP
epidermal growth factor/neuregulin signaling pathwayWIEP
ubiquitin/proteasome degradation pathwayWIDA
pathway pertinent to signaling in the brainWIDA

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
GnRH signaling pathway (04912)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Epithelial cell signaling in Helicobacter pylori infection (05120)Present in KEGG pathway Not present in KEGG pathwayNot present in KEGG pathway
Adherens junction (04520)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
VEGF signaling pathway (04370)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Tight junction (04530)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Gap junction (04540)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Focal adhesion (04510)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway