IpiRecord: IPI00622780

IPI00622780 - Aco1, CYTOPLASMIC ACONITASE.
Uniprot Accession: Q8VDC3
Uniprot ID: Q8VDC3_MOUSE
Mapping: Chr 4, 40331752 - 40387009
Entrez Gene: 11428
Entrez MapView: Geneprod
MGI: MGI:87879
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_5304)
Rat: Aco1, IRON-RESPONSIVE ELEMENT-BINDING PROTEIN 1.
Mouse: Aco1, CYTOPLASMIC ACONITASE.
Rat: Aco1, 99 KDA PROTEIN.
Human: ACO1, IRON-RESPONSIVE ELEMENT-BINDING PROTEIN 1.
Human: ACO1, ACONITASE 1, SOLUBLE.

Annotations for Aco1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
cytoplasmCNAS IDA TAS ISS ISS 
iron-sulfur cluster bindingFIEA 
iron ion bindingFIEA IEA IEA 
RNA bindingFNAS IDA IEA ISS IEA 
iron-responsive element bindingFIDA TAS ISS 
4 iron, 4 sulfur cluster bindingFIEA IEA IEA IEA 
metal ion bindingFIEA IEA IEA 
lyase activityFIEA IEA IEA 
aconitate hydratase activityFIDA IEA ISS IEA 
mRNA bindingFTAS 
cellular iron ion homeostasisPTAS ISS 
regulation of translationPTAS 
metabolic processPIEA IEA IEA 
tricarboxylic acid cyclePIEA IEA IEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (3)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
homeostasis/metabolism phenotypeMP#
lethality-embryonic/perinatalMP#
normal phenotypeMP#

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (3)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Citrate cycle (TCA cycle) (00020)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Glyoxylate and dicarboxylate metabolism (00630)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Reductive carboxylate cycle (CO2 fixation) (00720)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway