| IPI00623058 - Vcl, VINCULIN. | |
|---|---|
| Uniprot Accession: Q9ESQ3 | |
| Uniprot ID: Q9ESQ3_MOUSE | |
| Mapping: Chr 14, 19717950 - 19822228 | |
| Entrez Gene: 22330 | |
| Entrez MapView: |
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| MGI: MGI:98927 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_12185) |
|---|
| Rat: Vcl_predicted, SIMILAR TO VINCULIN. |
| Mouse: Vcl, VINCULIN. |
| Mouse: Vcl, VINCULIN. |
| Human: VCL, ISOFORM 1 OF VINCULIN. |
| Human: VCL, ISOFORM 2 OF VINCULIN. |
| Human: VCL, ISOFORM 3 OF VINCULIN. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| actin cytoskeleton | C | IEA | ||
| stress fiber | C | IDA | ||
| cell-matrix junction | C | ISS | ||
| plasma membrane | C | IDA | ||
| fascia adherens | C | IDA | ||
| actin filament | C | IDA | ||
| intercellular junction | C | IDA | ISS | |
| focal adhesion | C | IDA | ISS IDA | |
| costamere | C | IDA ISS | ISS | |
| protein complex | C | ISS | ||
| cytoskeleton | C | IEA | ||
| cytoplasm | C | IEA | ||
| adherens junction | C | IDA | ISS | |
| cell junction | C | IEA | ||
| oxidoreductase activity | F | RCA | ISS | |
| actin binding | F | IEA | ||
| protein binding | F | IPI | ISS | |
| alpha-catenin binding | F | ISS | ||
| structural molecule activity | F | IEA IEA | ||
| Rho GTPase binding | F | IPI | ||
| cell adhesion | P | IDA | ISS ISS | |
| apical junction assembly | P | ISS | ||
| regulation of cell migration | P | IDA | ISS | |
| metabolic process | P | RCA | ISS | |
| negative regulation of cell migration | P | ISS | ||
| lamellipodium biogenesis | P | IDA | ISS | |
| cell motility | P | ISS |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cellular phenotype | MP | Un | ||
| craniofacial phenotype | MP | Un | ||
| embryogenesis phenotype | MP | Un | ||
| lethality-embryonic/perinatal | MP | Un | ||
| muscle phenotype | MP | Un | ||
| nervous system phenotype | MP | Un | ||
| cardiovascular system phenotype | MP | Un | ||
| digestive/alimentary phenotype | MP | Un | ||
| limbs/digits/tail phenotype | MP | Un | ||
| growth/size phenotype | MP | Un | ||
| life span-post-weaning/aging | MP | Un |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Cardiomyopathy, Hypertrophic | D | ISS | ||
| Cardiomyopathy, Congestive | D | ISS |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Adherens junction (04520) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Leukocyte transendothelial migration (04670) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Regulation of actin cytoskeleton (04810) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Focal adhesion (04510) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |