IpiRecord: IPI00648818

IPI00648818 - Prkcz, PROTEIN KINASE C, ZETA.
Uniprot Accession: A2AD72
Uniprot ID: A2AD72_MOUSE
Mapping: Chr 4, 154103920 - 154205191
Entrez Gene: 18762
Entrez MapView: Geneprod
MGI: MGI:97602
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_5898)
Rat: Prkcz, PROTEIN KINASE C ZETA TYPE.
Mouse: Prkcz, PROTEIN KINASE C ZETA TYPE.
Mouse: Prkcz, PROTEIN KINASE C, ZETA ISOFORM B.
Mouse: Prkcz, PROTEIN KINASE C, ZETA.
Mouse: Prkcz, PROTEIN KINASE C, ZETA.
Mouse: Prkcz, PROTEIN KINASE C, ZETA.
Mouse: Prkcz, PROTEIN KINASE C, ZETA ISOFORM A.
Human: PRKCZ, PROTEIN KINASE C ZETA TYPE.
Human: PRKCZ, 14 KDA PROTEIN.
Human: PRKCZ, PROTEIN KINASE C, ZETA ISOFORM 2.
Human: PRKCZ, CONSERVED HYPOTHETICAL PROTEIN.
Human: PRKCZ, PROTEIN KINASE C, ZETA.

Annotations for Prkcz and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
plasma membraneCTAS ISS 
membrane fractionCTAS ISS 
endosomeCIEA IEA 
cell cortexCIDA ISS IEA 
cytoplasmCTAS IDA IDA ISS ISS IEA 
apical cortexCIDA ISS IEA 
tight junctionCIDA ISS IEA 
atypical protein kinase C activityFTAS IEA IDA ISS IEA 
protein serine/threonine kinase activityFIEA IEA IEA IEA 
ATP bindingFIEA IEA IEA IEA 
diacylglycerol bindingFIEA IEA IEA 
zinc ion bindingFIEA IEA IEA IEA 
metal ion bindingFIEA IEA IEA 
protein-tyrosine kinase activityFISS 
protein bindingFIPI IPI IPI ISS IDA 
kinase activityFIEA IEA 
nucleotide bindingFIEA IEA IEA 
protein kinase activityFIDA TAS ISS 
transferase activityFIEA IEA IEA 
microtubule cytoskeleton organization and biogenesisPIMP ISS IEA 
protein amino acid phosphorylationPTAS IEA IDA ISS ISS IEA 
intracellular signaling cascadePIEA IEA IDA IEA 
anti-apoptosisPTAS ISS 
signal transductionPIDA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (2)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
immune system phenotypeMPUn
hematopoietic system phenotypeMPUn

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Hypertrophy, Left VentricularDIED

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Type II diabetes mellitus (04930)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Tight junction (04530)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Insulin signaling pathway (04910)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway