IpiRecord: IPI00649993
| IPI00649993 - Pik3r3, PHOSPHATIDYLINOSITOL 3 KINASE, REGULATORY SUBUNIT, POLYPEPTIDE 3. | |
|---|---|
| Uniprot Accession: A2ADG3 | |
| Uniprot ID: A2ADG3_MOUSE | |
| Mapping: Chr 4, 115719846 - 115800988 | |
| Entrez Gene: 18710 | |
| Entrez MapView: |
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| MGI: MGI:109277 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_5880) |
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| Rat: Pik3r3, PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT GAMMA. |
| Mouse: Pik3r3, PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT GAMMA. |
| Mouse: Pik3r3, PHOSPHATIDYLINOSITOL 3 KINASE, REGULATORY SUBUNIT, POLYPEPTIDE 3. |
| Mouse: Pik3r3, PHOSPHATIDYLINOSITOL 3 KINASE, REGULATORY SUBUNIT, POLYPEPTIDE 3. |
| Human: PIK3R3, ISOFORM 2 OF PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT GAMMA. |
| Human: PIK3R3, ISOFORM 3 OF PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT GAMMA. |
| Human: PIK3R3, ISOFORM 1 OF PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT GAMMA. |
| Human: PIK3R3, PHOSPHOINOSITIDE-3-KINASE, REGULATORY SUBUNIT 3. |
Annotations for Pik3r3 and orthologs
GO Annotation Table
Compiled GO Annotations (from IPI)
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| phosphoinositide 3-kinase complex | C | IEA | IPI | ISS IEA |
| phosphoinositide 3-kinase regulator activity | F | IEA | IEA | |
| 1-phosphatidylinositol-3-kinase regulator activity | F | IDA | IDA ISS IEA | |
| kinase activity | F | IEA | IEA | |
| 1-phosphatidylinositol-3-kinase activity | F | ISS | ||
| protein binding | F | IPI | ISS ISS IEA | |
| intracellular signaling cascade | P | IEA | IEA | IEA |
| insulin receptor signaling pathway | P | IDA | ISS ISS IEA |
Cellular Component
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
Biological Process
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
Molecular Function
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
Phenotype (0)
There are no Mammalian Phenotype Ontology annotations for this protein in the database
Disease (0)
There are no Disease Ontology annotations for this protein in the database
Pathway (0)
There are no Pathway Ontology annotations for this protein in the database
KEGG Pathway (0)
KEGG Pathways for this protein (from IPI)
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Glioma (05214) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| T cell receptor signaling pathway (04660) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Chronic myeloid leukemia (05220) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| B cell receptor signaling pathway (04662) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| mTOR signaling pathway (04150) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Toll-like receptor signaling pathway (04620) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Fc epsilon RI signaling pathway (04664) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Apoptosis (04210) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Jak-STAT signaling pathway (04630) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| VEGF signaling pathway (04370) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Type II diabetes mellitus (04930) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Leukocyte transendothelial migration (04670) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Colorectal cancer (05210) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Regulation of actin cytoskeleton (04810) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Pancreatic cancer (05212) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Insulin signaling pathway (04910) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Natural killer cell mediated cytotoxicity (04650) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Focal adhesion (04510) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Phosphatidylinositol signaling system (04070) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
© MCW Proteomics Center, 2006-2008
Supported by funds from the National Heart, Lung and Blood Institute