| IPI00652220 - Prkca, CLONE:C230094C20 PRODUCT:SIMILAR TO PROTEIN KINASE C BETA 2. | |
|---|---|
| Uniprot Accession: Q3TQ39 | |
| Uniprot ID: Q3TQ39_MOUSE | |
| Mapping: Chr 11, 107754338 - 108159844 | |
| Entrez Gene: 18750 | |
| Entrez MapView: |
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| MGI: MGI:97595 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_10119) |
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| Rat: Prkca, PROTEIN KINASE C ALPHA TYPE. |
| Mouse: Prkca, PROTEIN KINASE C ALPHA TYPE. |
| Mouse: Prkca, CLONE:C230094C20 PRODUCT:SIMILAR TO PROTEIN KINASE C BETA 2. |
| Mouse: Prkca, 76 KDA PROTEIN. |
| Rat: Prkca, SIMILAR TO PROTEIN KINASE C ALPHA TYPE. |
| Rat: Prkca, 48 KDA PROTEIN. |
| Rat: Prkca, 68 KDA PROTEIN. |
| Rat: Prkca, 68 KDA PROTEIN. |
| Rat: Prkca, 66 KDA PROTEIN. |
| Human: PRKCA, PROTEIN KINASE C ALPHA TYPE. |
| Human: PRKCA, PRKCA PROTEIN. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| plasma membrane | C | IDA | ||
| cytoplasm | C | IDA IDA IDA IDA | ISS | |
| nucleus | C | IDA IDA | ISS | |
| membrane fraction | C | TAS | ISS IDA | |
| mitochondrion | C | IDA | ISS | |
| cytosol | C | IDA | ||
| synaptosome | C | IDA | ||
| ATP binding | F | IEA | IEA IEA | IEA |
| nucleotide binding | F | IEA | IEA | IEA |
| calcium-dependent protein kinase C activity | F | IDA | IDA ISS | |
| diacylglycerol binding | F | IEA | IEA | IEA |
| protein serine/threonine kinase activity | F | IDA | ISS IEA | |
| metal ion binding | F | IEA | ||
| calcium ion binding | F | IEA | IEA | IEA |
| protein kinase C activity | F | TAS | IDA IDA | ISS ISS IDA |
| protein binding | F | IPI | IPI | ISS ISS ISS IPI IPI |
| protein kinase activity | F | IEA | ||
| kinase activity | F | IEA | ||
| transferase activity | F | IEA | IEA | IEA |
| zinc ion binding | F | IEA | IEA | IEA |
| regulation of receptor mediated endocytosis | P | IMP | ||
| regulation of peptidyl-tyrosine phosphorylation | P | IMP | ISS | |
| regulation of progression through cell cycle | P | TAS | ISS | |
| peptidyl-serine phosphorylation | P | IDA | ||
| induction of apoptosis by intracellular signals | P | IMP | ISS | |
| neutrophil chemotaxis | P | IMP | ISS | |
| negative regulation of protein kinase activity | P | IMP | ISS | |
| inactivation of MAPK activity | P | IMP | ISS | |
| negative regulation of protein biosynthetic process | P | IMP | ||
| induction of positive chemotaxis | P | IMP | ISS | |
| protein amino acid phosphorylation | P | IEA | IDA | ISS IEA |
| cellular calcium ion homeostasis | P | IMP | ISS | |
| intracellular signaling cascade | P | IEA | IEA | IDA IEA |
| regulation of muscle contraction | P | IMP | ISS | |
| positive regulation of inflammatory response | P | IMP | ISS | |
| cardiac inotropy | P | IMP | ISS | |
| negative regulation of glucose import | P | IMP | ISS | |
| induction of apoptosis by extracellular signals | P | TAS | ISS | |
| cell surface receptor linked signal transduction | P | NR | ISS | |
| negative regulation of protein amino acid phosphorylation | P | IMP | ISS | |
| peptidyl-threonine phosphorylation | P | IDA | ||
| negative regulation of insulin receptor signaling pathway | P | IMP | ISS | |
| positive regulation of protein amino acid phosphorylation | P | IMP | ISS | |
| establishment of protein localization | P | TAS |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| skin/coat/nails phenotype | MP | Un | ||
| muscle phenotype | MP | Un | ||
| tumorigenesis | MP | Un | ||
| cardiovascular system phenotype | MP | Un | ||
| normal phenotype | MP | Un |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Hypertrophy, Left Ventricular | D | IED | ||
| Cardiomegaly | D | IAGP | ||
| Pituitary Neoplasms | D | ISS | ||
| Hypertrophy, Right Ventricular | D | IED | ||
| Cardiomyopathy, Congestive | D | ISS | ||
| Hypertension | D | IAGP |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| insulin signaling pathway | W | ISS |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Glioma (05214) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| GnRH signaling pathway (04912) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Long-term depression (04730) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Cholera - Infection (05110) | Present in KEGG pathway | Not present in KEGG pathway | Not present in KEGG pathway |
| Pathogenic Escherichia coli infection - EHEC (05130) | Present in KEGG pathway | Not present in KEGG pathway | Not present in KEGG pathway |
| Fc epsilon RI signaling pathway (04664) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| MAPK signaling pathway (04010) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Pathogenic Escherichia coli infection - EPEC (05131) | Present in KEGG pathway | Not present in KEGG pathway | Not present in KEGG pathway |
| VEGF signaling pathway (04370) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Leukocyte transendothelial migration (04670) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Tight junction (04530) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Wnt signaling pathway (04310) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Calcium signaling pathway (04020) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Gap junction (04540) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Natural killer cell mediated cytotoxicity (04650) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Focal adhesion (04510) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Long-term potentiation (04720) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Phosphatidylinositol signaling system (04070) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |