IpiRecord: IPI00719865

IPI00719865 - Nfkb1, ISOFORM 4 OF NUCLEAR FACTOR NF-KAPPA-B P105 SUBUNIT.
Uniprot Accession: P25799-4
Uniprot ID: NFKB1_MOUSE
Mapping: Chr 3, 135292997 - 135605172
Entrez Gene: 18033
Entrez MapView: Geneprod
MGI: MGI:97312
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_2865)
Rat: Nfkb1, SIMILAR TO NUCLEAR FACTOR NF-KAPPA-B P105 SUBUNIT.
Mouse: Nfkb1, ISOFORM 1 OF NUCLEAR FACTOR NF-KAPPA-B P105 SUBUNIT.
Mouse: Nfkb1, ISOFORM 2 OF NUCLEAR FACTOR NF-KAPPA-B P105 SUBUNIT.
Mouse: Nfkb1, ISOFORM 3 OF NUCLEAR FACTOR NF-KAPPA-B P105 SUBUNIT.
Mouse: Nfkb1, NF-KAPPA-B DNA-BINDING SUBUNIT (FRAGMENT).
Mouse: Nfkb1, ISOFORM 4 OF NUCLEAR FACTOR NF-KAPPA-B P105 SUBUNIT.
Mouse: Nfkb1, ISOFORM 5 OF NUCLEAR FACTOR NF-KAPPA-B P105 SUBUNIT.
Mouse: Nfkb1, ISOFORM 7 OF NUCLEAR FACTOR NF-KAPPA-B P105 SUBUNIT.
Mouse: Nfkb1, ISOFORM 6 OF NUCLEAR FACTOR NF-KAPPA-B P105 SUBUNIT.
Rat: Nfkb1, 97 KDA PROTEIN.
Human: NFKB1, ISOFORM 2 OF NUCLEAR FACTOR NF-KAPPA-B P105 SUBUNIT.
Human: NFKB1, ISOFORM 1 OF NUCLEAR FACTOR NF-KAPPA-B P105 SUBUNIT.

Annotations for Nfkb1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
cytosolCIDA 
cytoplasmCIEA IDA ISS 
protein complexCIDA 
nucleusCIDA IC IDA TAS ISS ISS IDA IEA 
double-stranded DNA bindingFIDA 
transcription factor activityFIEA TAS ISS 
transcription activator activityFIDA 
heat shock protein bindingFIPI 
protein bindingFIPI IPI IPI TAS ISS ISS IPI IPI IEA 
DNA bindingFIDA IDA IDA IDA IDA IDA ISS IEA 
sequence-specific DNA bindingFIDA 
actin bindingFIPI 
protein dimerization activityFIDA 
specific transcriptional repressor activityFIDA ISS 
positive regulation of transcriptionPISS 
apoptosisPIEA 
negative regulation of transcription, DNA-dependentPIDA ISS 
response to oxidative stressPIDA 
lymph node developmentPTAS ISS 
inflammatory responsePISS 
regulation of transcriptionPIEA 
response to bacteriumPISS 
transcriptionPIEA IEA 
transcription from RNA polymerase II promoterPISS 
regulation of transcription, DNA-dependentPIEA IEA IEA 
negative regulation of interleukin-12 biosynthetic processPIDA ISS 
anti-apoptosisPISS IMP 
signal transductionPIEA IEA 
positive regulation of transcription from RNA polymerase II promoterPIDA IDA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (8)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
skin/coat/nails phenotypeMPUn
homeostasis/metabolism phenotypeMPUn
immune system phenotypeMPUn
lethality-embryonic/perinatalMPUn
lethality-postnatalMPUn
nervous system phenotypeMPUn
normal phenotypeMPUn
hearing/vestibular/ear phenotypeMPUn

Disease (2)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
CardiomegalyDIEDIED
Aortic Aneurysm, AbdominalDIED

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
T cell receptor signaling pathway (04660)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Epithelial cell signaling in Helicobacter pylori infection (05120)Present in KEGG pathway Not present in KEGG pathwayNot present in KEGG pathway
Chronic myeloid leukemia (05220)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
B cell receptor signaling pathway (04662)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Toll-like receptor signaling pathway (04620)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Adipocytokine signaling pathway (04920)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Apoptosis (04210)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
MAPK signaling pathway (04010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Pancreatic cancer (05212)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway