| IPI00776050 - Cyp11b2, CYTOCHROME P450, FAMILY 11, SUBFAMILY B, POLYPEPTIDE 2. | |
|---|---|
| Uniprot Accession: Q14AB5 | |
| Uniprot ID: Q14AB5_MOUSE | |
| Mapping: Chr 15, 74678294 - 74683480 | |
| Entrez Gene: 13072 | |
| Entrez MapView: |
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| MGI: MGI:88584 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_7244) |
|---|
| Rat: Cyp11b2, CYTOCHROME P450 11B2, MITOCHONDRIAL PRECURSOR. |
| Mouse: Cyp11b2, CYTOCHROME P450 11B2, MITOCHONDRIAL PRECURSOR. |
| Mouse: Cyp11b2, CYTOCHROME P450, FAMILY 11, SUBFAMILY B, POLYPEPTIDE 2. |
| Human: CYP11B2, CYTOCHROME P450 11B2, MITOCHONDRIAL PRECURSOR. |
| Human: CYP11B2, STEROID 18-HYDROXYLASE (FRAGMENT). |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| dendrite | C | IDA | ||
| membrane | C | IEA | IEA | IEA |
| mitochondrion | C | IEA | IEA IEA | IEA |
| oxidoreductase activity | F | IEA | ||
| oxygen binding | F | NR | ISS | |
| monooxygenase activity | F | IEA | IEA IEA | IEA |
| iron ion binding | F | IEA | IEA IEA | IEA |
| corticosterone 18-monooxygenase activity | F | IEA | IEA | IDA IEA IDA |
| metal ion binding | F | IEA | IEA | IEA |
| steroid 11-beta-monooxygenase activity | F | TAS | IDA IDA | IDA ISS IEA |
| heme binding | F | IEA | IEA | IEA |
| electron transport | P | IEA | IEA | IEA |
| regulation of blood pressure by circulatory renin-angiotensin | P | IMP | ISS IEA | |
| drinking behavior | P | IMP | ISS IEA | |
| lipid metabolic process | P | IEA | ||
| aldosterone mediated regulation of body fluids | P | IMP | ISS IEA | |
| steroid metabolic process | P | IEA | ||
| C21-steroid hormone biosynthetic process | P | IEA | IEA | IDA IEA |
| ion homeostasis | P | IMP | ISS IEA | |
| aldosterone biosynthetic process | P | IDA IDA | ||
| blood pressure regulation | P | TAS | ISS | |
| glucocorticoid biosynthetic process | P | TAS | ISS |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| growth/size phenotype | MP | Un | ||
| endocrine/exocrine gland phenotype | MP | Un | ||
| homeostasis/metabolism phenotype | MP | Un | ||
| cardiovascular system phenotype | MP | Un | ||
| lethality-postnatal | MP | Un | ||
| decreased urine output | N | IAGP | ||
| increased circulating corticosterone level | N | IAGP | ||
| abnormal adrenal gland morphology | N | IAGP | ||
| increased circulating aldosterone level | N | IAGP | ||
| small thymus | N | IAGP | ||
| decreased left ventricle weight | N | IAGP |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Cardiomyopathy, Hypertrophic | D | ISS | ||
| Hypertrophy, Left Ventricular | D | ISS | ||
| Hyperaldosteronism | D | ISS | ||
| Pre-Eclampsia | D | ISS | ||
| Hypoaldosteronism | D | ISS | ||
| Hypertension | D | ISS |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| C21-Steroid hormone metabolic pathway | W | IEA IDA | ||
| androgen and estrogen metabolic pathway | W | IEA |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| C21-Steroid hormone metabolism (00140) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Androgen and estrogen metabolism (00150) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |