IpiRecord: IPI00785237

IPI00785237 - Nfatc3, CYTOPLASMIC NUCLEAR FACTOR OF ACTIVATED T-CELLS 3.
Uniprot Accession: Q8C2J3
Uniprot ID: Q8C2J3_MOUSE
Mapping: Chr 8, 108948972 - 109017574
Entrez Gene: 18021
Entrez MapView: Geneprod
MGI: MGI:103296
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_14098)
Rat: Nfatc3_predicted, SIMILAR TO CYTOPLASMIC NUCLEAR FACTOR OF ACTIVATED T-CELLS 3.
Mouse: Nfatc3, ISOFORM X1 OF NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 3.
Mouse: Nfatc3, ISOFORM X2 OF NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 3.
Mouse: Nfatc3, ISOFORM DELTA-X OF NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 3.
Mouse: Nfatc3, MKIAA4144 PROTEIN (FRAGMENT).
Mouse: Nfatc3, CYTOPLASMIC, CALCINEURIN-DEPENDENT 3, FULL INSERT SEQUENCE.
Mouse: Nfatc3, CYTOPLASMIC NUCLEAR FACTOR OF ACTIVATED T-CELLS 3.
Rat: Nfatc3_predicted, 115 KDA PROTEIN.
Rat: Nfatc3_predicted, 61 KDA PROTEIN.
Human: NFATC3, ISOFORM 2 OF NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 3.
Human: NFATC3, ISOFORM 1 OF NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 3.
Human: NFATC3, ISOFORM 3 OF NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 3.
Human: NFATC3, ISOFORM 4 OF NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 3.
Human: NFATC3, ISOFORM 5 OF NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 3.
Human: NFATC3, ISOFORM 6 OF NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 3.
Human: NFATC3, (FRAGMENT).

Annotations for Nfatc3 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
nucleusCIEA IDA IDA IDA 
cytoplasmCIDA IDA IDA 
cytosolCIDA 
DNA bindingFIDA 
transcription factor activityFIEA IDA 
protein bindingFIPI 
regulation of transcriptionPIEA 
heart developmentPIGI 
positive regulation of transcription, DNA-dependentPIMP 
transcriptionPIEA 
cellular respirationPIMP 
regulation of transcription, DNA-dependentPIEA IMP IDA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (14)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
behavior/neurological phenotypeMPUn
endocrine/exocrine gland phenotypeMPUn
homeostasis/metabolism phenotypeMPUn
immune system phenotypeMPUn
embryogenesis phenotypeMPUn
lethality-embryonic/perinatalMPUn
muscle phenotypeMPUn
nervous system phenotypeMPUn
respiratory system phenotypeMPUn
vision/eye phenotypeMPUn
cardiovascular system phenotypeMPUn
digestive/alimentary phenotypeMPUn
hematopoietic system phenotypeMPUn
growth/size phenotypeMPUn

Disease (2)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Hypertrophy, Left VentricularDISS
Hypertrophy, Right VentricularDISS

Pathway (3)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
endothelin signaling pathwayWIMP
calcineurin signaling pathwayWISS
nuclear factor of activated T-cells signaling pathwayWISS

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
T cell receptor signaling pathway (04660)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
B cell receptor signaling pathway (04662)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
VEGF signaling pathway (04370)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Wnt signaling pathway (04310)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Axon guidance (04360)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Natural killer cell mediated cytotoxicity (04650)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway