IpiRecord: IPI00830951

IPI00830951 - Kras, 4 KDA PROTEIN.
Uniprot Accession: -NA-
Uniprot ID: -NA-
Mapping: Chr 6, 145173866 - 145207390
Entrez Gene: 16653
Entrez MapView: Geneprod
MGI: MGI:96680
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_5111)
Rat: Kras, ISOFORM 2A OF GTPASE KRAS PRECURSOR.
Mouse: Kras, ISOFORM 2A OF GTPASE KRAS PRECURSOR.
Mouse: Kras, ISOFORM 2B OF GTPASE KRAS PRECURSOR.
Mouse: Kras, 4 KDA PROTEIN.
Mouse: Kras, 4 KDA PROTEIN.
Rat: Kras, ISOFORM 2B OF GTPASE KRAS PRECURSOR.
Human: KRAS, KRAS PROTEIN.
Human: KRAS, ISOFORM 2A OF GTPASE KRAS PRECURSOR.
Human: KRAS, ISOFORM 2B OF GTPASE KRAS PRECURSOR.
Human: KRAS, 8 KDA PROTEIN.
Human: KRAS, K-RAS PROTEIN.

Annotations for Kras and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
membrane fractionCIDA ISS 
intracellularCIEA 
membraneCIEA 
lipid raftCIDA 
GMP bindingFIDA 
GTP bindingFIEA IEA IEA 
protein bindingFIPI 
LRR domain bindingFIDA 
GTPase activityFTAS IGI ISS 
GDP bindingFIDA 
nucleotide bindingFIEA IEA 
regulation of progression through cell cyclePIEA 
activation of NF-kappaB transcription factorPIMP 
regulation of synaptic transmission, GABAergicPIGI 
striated muscle cell differentiationPIGI ISS 
positive regulation of MAPK activityPIMP 
regulation of long-term neuronal synaptic plasticityPIGI 
actin cytoskeleton organization and biogenesisPIGI 
positive regulation of nitric-oxide synthase activityPIMP 
Ras protein signal transductionPIGI TAS ISS 
visual learningPIGI 
response to glucocorticoid stimulusPIEP IEP 
response to mineralocorticoid stimulusPIEP 
negative regulation of neuron apoptosisPIGI 
cytokine and chemokine mediated signaling pathwayPIMP 
positive regulation of cell proliferationPIGI 
positive regulation of Rac protein signal transductionPIGI 
small GTPase mediated signal transductionPIEA IEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (23)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
skin/coat/nails phenotypeMPUn Un Un
cellular phenotypeMPUn Un Un Un Un
behavior/neurological phenotypeMPUn
homeostasis/metabolism phenotypeMPUn Un
endocrine/exocrine gland phenotypeMPUn Un
immune system phenotypeMPUn
embryogenesis phenotypeMPUn Un Un Un
lethality-embryonic/perinatalMPUn Un Un Un Un
lethality-postnatalMPUn Un
muscle phenotypeMPUn Un
nervous system phenotypeMPUn Un
respiratory system phenotypeMPUn Un
vision/eye phenotypeMPUn Un
tumorigenesisMPUn Un Un
limbs/digits/tail phenotypeMPUn
cardiovascular system phenotypeMPUn Un Un Un Un
normal phenotypeMPUn Un
digestive/alimentary phenotypeMPUn Un
hematopoietic system phenotypeMPUn Un Un
growth/size phenotypeMPUn Un Un Un
liver/biliary system phenotypeMPUn Un Un
life span-post-weaning/agingMPUn Un Un
no phenotypic analysisMPUn

Disease (16)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Pancreatic NeoplasmsDISS
Stomach NeoplasmsDISS
Abnormalities, MultipleDISSISS
Kidney Failure, ChronicDIED
Breast NeoplasmsDISS
Lung NeoplasmsDISS
Endometrial NeoplasmsDIAGP
Sarcoma, ExperimentalDIAGP
Noonan SyndromeDISS
Multiple MyelomaDISS
Bladder NeoplasmsDISS
Mental RetardationDISSISS
Cardiomyopathy, CongestiveDISS
AstrocytomaDISS
Leukemia, Myelocytic, AcuteDISS
HypertensionDISS

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Glioma (05214)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
GnRH signaling pathway (04912)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
T cell receptor signaling pathway (04660)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Long-term depression (04730)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Chronic myeloid leukemia (05220)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
B cell receptor signaling pathway (04662)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Fc epsilon RI signaling pathway (04664)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
MAPK signaling pathway (04010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
VEGF signaling pathway (04370)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Tight junction (04530)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Colorectal cancer (05210)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Regulation of actin cytoskeleton (04810)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Axon guidance (04360)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Gap junction (04540)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Dorso-ventral axis formation (04320)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Pancreatic cancer (05212)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Insulin signaling pathway (04910)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Natural killer cell mediated cytotoxicity (04650)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Long-term potentiation (04720)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway