IpiRecord: IPI00830969

IPI00830969 - Itgb2, 15 KDA PROTEIN.
Uniprot Accession: -NA-
Uniprot ID: -NA-
Mapping: Chr 10, 76985685 - 77009099
Entrez Gene: 16414
Entrez MapView: Geneprod
MGI: MGI:96611
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_14275)
Rat: Itgb2, INTEGRIN BETA.
Mouse: Itgb2, INTEGRIN BETA-2 PRECURSOR.
Mouse: Itgb2, FULL INSERT SEQUENCE.
Mouse: Itgb2, 15 KDA PROTEIN.
Mouse: Itgb2, 6 KDA PROTEIN.
Human: ITGB2, INTEGRIN BETA.
Human: ITGB2, INTEGRIN BETA-2 PRECURSOR.
Human: ITGB2, CDNA FLJ40545 FIS, CLONE THYMU2001195.
Human: ITGB2, INTEGRIN BETA CHAIN, BETA 2 VARIANT (FRAGMENT).
Human: ITGB2, 11 KDA PROTEIN.

Annotations for Itgb2 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
plasma membraneCIDA 
integral to membraneCIEA RCA ISS IEA 
membraneCIEA IEA IEA 
integrin complexCIEA NAS IEA ISS IEA 
cell surfaceCIDA IDA 
receptor activityFIEA IEA IEA IEA 
cell adhesion molecule bindingFIMP 
bindingFIEA 
protein heterodimerization activityFIPI 
protein bindingFIEA IPI IEA ISS 
protein kinase bindingFIPI ISS 
endothelial cell migrationPIMP 
inflammatory responsePNAS ISS 
activation of NF-kappaB transcription factorPIMP 
neutrophil chemotaxisPIDA IMP ISS ISS 
cell-matrix adhesionPIEA IEA IEA 
regulation of peptidyl-tyrosine phosphorylationPIDA ISS 
positive regulation of angiogenesisPIMP 
cell-cell signalingPNAS ISS 
leukocyte adhesionPIDA ISS IMP 
apoptosisPNAS ISS 
positive regulation of nitric oxide biosynthetic processPIMP 
cell-cell adhesionPIMP IMP 
activated T cell proliferationPIMP ISS 
leukocyte migration during inflammatory responsePIMP 
integrin-mediated signaling pathwayPIEA NAS IDA ISS ISS IEA 
cell adhesionPIEA TAS IMP ISS ISS 
regulation of cell shapePNAS ISS 
natural killer cell activationPIMP 
multicellular organismal developmentPIEA IEA 
cellular extravasationPIMP IMP ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (6)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
skin/coat/nails phenotypeMPUn
lethality-embryonic/perinatalMPUn
immune system phenotypeMPUn
vision/eye phenotypeMPUn
hematopoietic system phenotypeMPUn
pigmentation phenotypeMPUn

Disease (2)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Coronary RestenosisDISS
Leukocyte-Adhesion Deficiency SyndromeDISS

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
integrin signaling pathwayWISS

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Cell adhesion molecules (CAMs) (04514)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Leukocyte transendothelial migration (04670)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Regulation of actin cytoskeleton (04810)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Natural killer cell mediated cytotoxicity (04650)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway