IpiRecord: IPI00845853

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
endoplasmic reticulum	C			IEA
mitochondrion	C			ISS IDA IEA
cytosol	C			ISS IEA
nucleus	C			IEA
membrane	C			IEA
integral to membrane	C			IEA
nuclear membrane	C			IEA
mitochondrial outer membrane	C			ISS IEA
cytoplasm	C			IDA
protein binding	F			ISS IPI IEA
protein heterodimerization activity	F			IEA
protease binding	F			IEA
protein homodimerization activity	F			IEA
BH3 domain binding	F			IEA
identical protein binding	F			ISS
response to hypoxia	P			IEP
response to organic substance	P			IEP
response to peptide hormone stimulus	P			IEP
negative regulation of neuron apoptosis	P			IEA
negative regulation of apoptosis	P			ISS
regulation of protein heterodimerization	P			IEA
negative regulation of cell proliferation	P			ISS
regulation of progression through cell cycle	P			ISS IEA
response to nutrient	P			IEP
humoral immune response	P			ISS
regulation of mitochondrial membrane potential	P			ISS
response to nicotine	P			IEP IEA
negative regulation of cellular pH reduction	P			IEA
apoptosis	P			TAS ISS
regulation of protein homodimerization	P			IEA
regulation of mitochondrial membrane permeability	P			ISS
defense response to virus	P			IEA
anti-apoptosis	P			IDA ISS ISS IMP IEA
response to heat	P			IEP
response to iron ion	P			IEA
response to caffeine	P			IEP
response to inorganic substance	P			IEP
response to ethanol	P			IEP
response to estrogen stimulus	P			IEP
release of cytochrome c from mitochondria	P			ISS ISS ISS

Cellular Component

Biological Process

Molecular Function

Phenotype (2)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
??	N			IED
abnormal renal tubule morphology	N			IED

Disease (6)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Diabetes Mellitus, Experimental	D			IEP
Glomerulonephritis	D			IED
Impotence	D			IED
Myocardial Reperfusion Injury	D			IEP
Carcinoma, Squamous Cell	D			IEP
Lymphoma, Follicular	D			ISS

Pathway (3)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
intrinsic apoptotic pathway	W			ISS
programmed cell death pathway	W			IEA
amyotrophic lateral sclerosis disease pathway	W			IEA

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Prion disease (05060)	Present in KEGG pathway	Not present in KEGG pathway	Present in KEGG pathway
Apoptosis (04210)	Present in KEGG pathway	Not present in KEGG pathway	Present in KEGG pathway
Amyotrophic lateral sclerosis (ALS) (05030)	Present in KEGG pathway	Not present in KEGG pathway	Present in KEGG pathway
Colorectal cancer (05210)	Present in KEGG pathway	Not present in KEGG pathway	Present in KEGG pathway
Focal adhesion (04510)	Present in KEGG pathway	Not present in KEGG pathway	Present in KEGG pathway
Neurodegenerative Disorders (01510)	Present in KEGG pathway	Not present in KEGG pathway	Present in KEGG pathway