IpiRecord: IPI00853849

IPI00853849 - Fgf2, FGF2 (FRAGMENT).
Uniprot Accession: Q7TPH0
Uniprot ID: Q7TPH0_MOUSE
Mapping: Chr 3, 37540399 - 37596346
Entrez Gene: 14173
Entrez MapView: Geneprod
MGI: MGI:95516
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_2336)
Rat: Fgf2, HEPARIN-BINDING GROWTH FACTOR 2 PRECURSOR.
Mouse: Fgf2, HEPARIN-BINDING GROWTH FACTOR 2 PRECURSOR.
Mouse: Fgf2, FIBROBLAST GROWTH FACTOR 2.
Mouse: Fgf2, 13 KDA PROTEIN.
Mouse: Fgf2, FIBROBLAST GROWTH FACTOR 2.
Mouse: Fgf2, FIBROBLAST GROWTH FACTOR 2.
Mouse: Fgf2, FIBROBLAST GROWTH FACTOR 2.
Mouse: Fgf2, FGF2 (FRAGMENT).
Rat: Fgf2, 13 KDA PROTEIN.
Human: FGF2, FIBROBLAST GROWTH FACTOR 2.

Annotations for Fgf2 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
extracellular spaceCTAS IDA IDA ISS ISS 
extracellular regionCTAS ISS 
fibroblast growth factor receptor bindingFIEA 
heparin bindingFIEA IEA IEA 
growth factor activityFIEA IDA ISS IEA 
voltage-gated calcium channel activityFIDA 
nerve growth factor receptor bindingFTAS 
protein bindingFIPI IPI ISS ISS ISS 
activation of MAPK activityPTAS ISS 
positive regulation of cell differentiationPIEA IDA ISS 
positive regulation of protein amino acid phosphorylationPIEA IDA ISS 
nervous system developmentPTAS ISS 
protein kinase cascadePIDA 
positive regulation of epithelial cell proliferationPIDA 
positive regulation of granule cell precursor proliferationPIEA IDA 
regulation of retinal programmed cell deathPIEA IDA ISS 
activation of MAPKK activityPIEA IDA ISS 
negative regulation of cell proliferationPIEA IGI 
negative regulation of transcription, DNA-dependentPIDA 
muscle developmentPNR ISS 
C21-steroid hormone biosynthetic processPIDA 
positive regulation of cell proliferationPIGI IDA IGI IDA ISS ISS 
regulation of progression through cell cyclePIEA IEA IEA 
positive regulation of angiogenesisPIEA IGI IDA 
positive regulation of transcriptionPIDA 
glial cell differentiationPIEA IMP ISS 
synaptic transmissionPIDA 
lung developmentPIEA IGI IDA ISS 
negative regulation of cell growthPIDA 
cell differentiationPIEA IEA 
regulation of calcium ion-dependent exocytosisPIDA 
cell proliferationPIEA IEA IEA 
regulation of transcription, DNA-dependentPIDA 
signal transductionPNAS IEA IDA ISS 
cell-cell signalingPNR ISS 
Ras protein signal transductionPTAS ISS 
chemotaxisPTAS ISS 
organ morphogenesisPTAS ISS 
induction of an organPIEA IDA ISS 
angiogenesisPIEA IGI IDA IDA ISS IEA 
nuclear translocation of MAPKPIDA 
multicellular organismal developmentPIEA IEA IEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (13)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
cellular phenotypeMPUn
behavior/neurological phenotypeMPUn
homeostasis/metabolism phenotypeMPUn
skeleton phenotypeMPUn
muscle phenotypeMPUn
nervous system phenotypeMPUn Un
hearing/vestibular/ear phenotypeMPUn Un
normal phenotypeMPUn
cardiovascular system phenotypeMPUn Un
hematopoietic system phenotypeMPUn
abnormal cerebral cortex morphologyNIEA
decreased motor neuron numberNIEA
decreased bone densityNIEA

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
MAPK signaling pathway (04010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Regulation of actin cytoskeleton (04810)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway