| IPI00857195 - Itgav, INTEGRIN ALPHA V. | |
|---|---|
| Uniprot Accession: A2AKI6 | |
| Uniprot ID: A2AKI6_MOUSE | |
| Mapping: Chr 2, 83525354 - 83604646 | |
| Entrez Gene: 16410 | |
| Entrez MapView: |
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| MGI: MGI:96608 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_3375) |
|---|
| Rat: Itgav_predicted, 110 KDA PROTEIN. |
| Mouse: Itgav, INTEGRIN ALPHA-V PRECURSOR. |
| Mouse: Itgav, INTEGRIN ALPHA V. |
| Mouse: Itgav, INTEGRIN ALPHA V. |
| Mouse: Itgav, INTEGRIN ALPHA V. |
| Mouse: Itgav, INTEGRIN ALPHA V. |
| Rat: Itgav_predicted, SIMILAR TO INTEGRIN ALPHA-V PRECURSOR. |
| Rat: Itgav_predicted, 102 KDA PROTEIN. |
| Rat: Itgav_predicted, PROTEIN. |
| Rat: Itgav_predicted, SIMILAR TO INTEGRIN ALPHA-V PRECURSOR. |
| Rat: Itgav_predicted, 109 KDA PROTEIN. |
| Human: ITGAV, ISOFORM 1 OF INTEGRIN ALPHA-V PRECURSOR. |
| Human: ITGAV, ISOFORM 2 OF INTEGRIN ALPHA-V PRECURSOR. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| integrin complex | C | IEA | ISS IC IEA | |
| plasma membrane | C | IDA | ||
| membrane | C | IEA | ||
| integral to membrane | C | IEA | ||
| protein binding | F | IEA | ISS | |
| protein heterodimerization activity | F | IC | ||
| receptor activity | F | IEA | ||
| calcium ion binding | F | IEA | IEA | |
| peptide binding | F | IDA | ||
| positive regulation of MAPKKK cascade | P | IDA | ||
| cell differentiation | P | IEA | ||
| cellular calcium ion homeostasis | P | IDA | ||
| cell-matrix adhesion | P | ISS | ||
| positive regulation of cell proliferation | P | IDA | ||
| blood vessel development | P | IMP | ||
| integrin-mediated signaling pathway | P | IEA | ISS IDA | |
| cell adhesion | P | IEA IEA | ISS IDA IEA | |
| angiogenesis | P | IEA | IEP | |
| cell migration | P | IMP | ||
| elevation of cytosolic calcium ion concentration | P | IDA | ||
| vasculogenesis | P | IEP | ||
| multicellular organismal development | P | IEA |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| craniofacial phenotype | MP | Un | ||
| homeostasis/metabolism phenotype | MP | Un | ||
| embryogenesis phenotype | MP | Un | ||
| lethality-embryonic/perinatal | MP | Un | ||
| skeleton phenotype | MP | Un | ||
| muscle phenotype | MP | Un | ||
| nervous system phenotype | MP | Un | ||
| cardiovascular system phenotype | MP | Un | ||
| digestive/alimentary phenotype | MP | Un | ||
| growth/size phenotype | MP | Un |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Corneal Neovascularization | D | IED | ||
| Metabolic Syndrome X | D | ISS | ||
| Coronary Stenosis | D | ISSIED | ||
| Ischemia | D | ISSIED | ||
| Retinal Neovascularization | D | ISS | ||
| Cerebral Hemorrhage | D | ISS | ||
| Myocardial Ischemia | D | ISS | ||
| Hyperglycemia | D | ISS | ||
| Aortic Aneurysm, Abdominal | D | ISS | ||
| Hypertension | D | IEP | ||
| Choroidal Neovascularization | D | IED |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| integrin signaling pathway | W | ISSIDA |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| ECM-receptor interaction (04512) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Cell adhesion molecules (CAMs) (04514) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Regulation of actin cytoskeleton (04810) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Focal adhesion (04510) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |