| IPI00188164 - Gad1, GLUTAMATE DECARBOXYLASE 1. | |
|---|---|
| Uniprot Accession: P18088 | |
| Uniprot ID: DCE1_RAT | |
| Mapping: Chr 3, 52789370 - 52830036 | |
| Entrez Gene: 24379 | |
| Entrez MapView: |
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| RGD: 2652 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_3267) |
|---|
| Rat: Gad1, GLUTAMATE DECARBOXYLASE 1. |
| Mouse: Gad1, GLUTAMATE DECARBOXYLASE 1. |
| Mouse: Gad1, INSERT SEQUENCE. |
| Rat: Gad1, GLUTAMATE DECARBOXYLASE. |
| Human: GAD1, ISOFORM 1 OF GLUTAMATE DECARBOXYLASE 1. |
| Human: GAD1, GAD1 PROTEIN. |
| Human: GAD1, ISOFORM 3 OF GLUTAMATE DECARBOXYLASE 1. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cytoplasm | C | IDA | ISS | |
| synapse | C | IDA | ISS | |
| vesicle membrane | C | ISS | ||
| mitochondrion | C | IDA | ISS | |
| intracellular | C | ISS ISS | ||
| axon | C | IDA | ISS | |
| pyridoxal phosphate binding | F | IEA | IEA | IEA |
| carboxy-lyase activity | F | IEA | IEA IEA | |
| catalytic activity | F | IEA | ||
| lyase activity | F | IEA | IEA | IEA |
| protein binding | F | ISS ISS | ||
| glutamate decarboxylase activity | F | IEA | IEA IDA ISS ISS | |
| synaptic transmission | P | IEA | IEA ISS | |
| glutamate decarboxylation to succinate | P | ISS | ||
| protein-pyridoxal-5-phosphate linkage | P | ISS | ||
| neurotransmitter biosynthetic process | P | IEA | IEA | |
| carboxylic acid metabolic process | P | IEA | IEA | IEA |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| craniofacial phenotype | MP | Un Un Un | ||
| growth/size phenotype | MP | Un | ||
| behavior/neurological phenotype | MP | Un Un | ||
| homeostasis/metabolism phenotype | MP | Un | ||
| embryogenesis phenotype | MP | Un | ||
| lethality-embryonic/perinatal | MP | Un Un Un | ||
| digestive/alimentary phenotype | MP | Un Un | ||
| skeleton phenotype | MP | Un | ||
| nervous system phenotype | MP | Un Un | ||
| respiratory system phenotype | MP | Un Un | ||
| life span-post-weaning/aging | MP | Un | ||
| perinatal lethality | N | ISS | ||
| cleft palate | N | ISS |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| beta-alanine metabolic pathway | W | IEA | ||
| alanine and aspartate metabolic pathway | W | IEA | ||
| glutamate metabolic pathway | W | IEA | ||
| taurine and hypotaurine metabolic pathway | W | IEA | ||
| butanoate metabolic pathway | W | IEA |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| beta-Alanine metabolism (00410) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Taurine and hypotaurine metabolism (00430) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Glutamate metabolism (00251) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Type I diabetes mellitus (04940) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Butanoate metabolism (00650) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Alanine and aspartate metabolism (00252) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |