IpiRecord: IPI00188697

IPI00188697 - Cd74, ISOFORM LONG OF H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN GAMMA CHAIN.
Uniprot Accession: P10247-1
Uniprot ID: HG2A_RAT
Mapping: Chr 18, 56756511 - 56765713
Entrez Gene: 25599
Entrez MapView: Geneprod
RGD: 2313
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_13649)
Rat: Cd74, ISOFORM LONG OF H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN GAMMA CHAIN.
Mouse: Cd74, ISOFORM LONG OF H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN GAMMA CHAIN.
Mouse: Cd74, ISOFORM SHORT OF H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN GAMMA CHAIN.
Mouse: Cd74, 24 KDA PROTEIN.
Rat: Cd74, ISOFORM SHORT OF H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN GAMMA CHAIN.
Human: CD74, ISOFORM LONG OF HLA CLASS II HISTOCOMPATIBILITY ANTIGEN GAMMA CHAIN.
Human: CD74, ISOFORM SHORT OF HLA CLASS II HISTOCOMPATIBILITY ANTIGEN GAMMA CHAIN.
Human: CD74, CD74 ANTIGEN ISOFORM C.

Annotations for Cd74 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
integral to plasma membraneCTAS ISS 
lysosomeCIDA IDA ISS 
plasma membraneCIDA IDA IMP IMP ISS 
Golgi apparatusCIDA ISS 
integral to membraneCIEA TAS 
membraneCIEA IEA IEA 
late endosomeCIDA ISS 
external side of plasma membraneCIDA ISS 
endoplasmic reticulumCIDA ISS 
multivesicular bodyCIDA ISS 
protein bindingFIPI IPI IDA ISS 
MHC class II protein bindingFIEA IEA 
protein foldingPIEA 
negative thymic T cell selectionPIMP ISS 
defense responsePIMP IMP ISS 
activation of MAPK activityPIDA 
negative regulation of T cell differentiationPIMP ISS 
positive regulation of T cell differentiationPIMP IMP IMP ISS 
chaperone cofactor-dependent protein foldingPIDA IMP ISS 
cell proliferationPIDA 
antigen processing and presentationPIEA IDA IMP IDA ISS 
antigen processing and presentation of exogenous peptide antigen via MHC class IIPIMP IMP ISS 
protein complex assemblyPIDA ISS 
immune responsePIEA IEA IEA 
positive thymic T cell selectionPIMP IMP IMP ISS 
intracellular protein transportPIEA IDA IDA IMP ISS 
immunoglobulin mediated immune responsePIMP ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (4)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
immune system phenotypeMPUn Un Un Un
hematopoietic system phenotypeMPUn Un Un
growth/size phenotypeMPUn Un
life span-post-weaning/agingMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Antigen processing and presentation (04612)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway