IpiRecord: IPI00189531

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
presynaptic membrane	C			IDA
plasma membrane	C	IDA	ISS	IDA
extracellular space	C		RCA	ISS
postsynaptic membrane	C	IEA	IEA IEA	IEA
growth cone	C			IDA
nicotinic acetylcholine-gated receptor-channel complex	C	TAS		TAS ISS IDA
cytoplasm	C			IDA
external side of plasma membrane	C		IDA
asymmetric synapse	C			IDA
membrane fraction	C		IDA
synapse	C	IEA	IEA
membrane	C		IEA IEA
axon	C			IDA IDA
postsynaptic density	C			IDA
dendritic spine	C			IDA
dendritic shaft	C			IDA
apical plasma membrane	C		IDA
lipid raft	C			IDA
cell junction	C	IEA	IEA
integral to membrane	C	IEA	RCA	ISS IEA
cell soma	C			IDA
receptor activity	F		IEA	IEA
acetylcholine receptor activity	F	TAS		ISS
adenylate cyclase binding	F			IPI
acetylcholine binding	F			IMP
protein binding	F	IPI	IPI	ISS ISS IPI
neurotransmitter receptor activity	F	IEA	IEA	IEA
drug binding	F			IDA
extracellular ligand-gated ion channel activity	F	IEA	IEA	IEA
nicotinic acetylcholine-activated cation-selective channel activity	F	TAS IEA	RCA IMP ISS IMP IDA IMP	IDA ISS ISS IDA IEA IMP IMP
ion channel activity	F	IEA	IEA IEA	IEA
response to nicotine	P		IMP IMP
synaptic transmission	P	NR		ISS
dopamine biosynthetic process	P			IEP
calcium ion transport	P		ISS	IMP
associative learning	P		IGI IMP
negative regulation of interleukin-6 production	P		IMP
response to food	P		IMP
behavioral response to ethanol	P		IMP
negative regulation of tumor necrosis factor production	P	IDA	ISS IMP IMP
regulation of membrane potential	P		IMP IMP ISS
activation of MAPK activity	P	TAS		ISS
negative regulation of inflammatory response	P		IMP
menstrual cycle	P		IMP
positive regulation of heart contraction rate in baroreceptor response to decreased blood pressure	P		IMP
B cell activation	P		IMP IMP
sperm motility	P		IMP
negative regulation of interleukin-1 beta production	P		IMP
generation of action potential	P			IMP
transport	P		IEA IEA
synaptic transmission, cholinergic	P		IMP	IMP
regulation of synaptic transmission, dopaminergic	P		IMP
T cell activation	P		IMP
memory	P		IMP
regulation of inflammatory response	P		IMP
regulation of norepinephrine secretion	P		IMP
generation of menstrual cycle rhythm	P		IMP
ion transport	P	IEA	IMP IMP	IEA
signal transduction	P	NAS		ISS
response to ethanol	P		IMP

Cellular Component

Biological Process

Molecular Function

Phenotype (4)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
behavior/neurological phenotype	MP		Un
homeostasis/metabolism phenotype	MP		Un
immune system phenotype	MP		Un
nervous system phenotype	MP		Un

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
??	D			ISS

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Calcium signaling pathway (04020)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway