IpiRecord: IPI00190352

IPI00190352 - Ccnd1, G1/S-SPECIFIC CYCLIN-D1.
Uniprot Accession: Q99NB4
Uniprot ID: Q99NB4_RAT
Mapping: Chr 1, 205360031 - 205366632
Entrez Gene: 58919
Entrez MapView: Geneprod
RGD: 68384
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_1468)
Rat: Ccnd1, G1/S-SPECIFIC CYCLIN-D1.
Mouse: Ccnd1, G1/S-SPECIFIC CYCLIN-D1.
Human: CCND1, G1/S-SPECIFIC CYCLIN-D1.
Human: CCND1, CYCLIN D1 (FRAGMENT).

Annotations for Ccnd1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
cellular_componentCND 
cytosolCIEA IDA ISS IEA 
cyclin-dependent protein kinase holoenzyme complexCIEA IPI ISS IEA 
nucleusCIEA IDA ISS IEA 
intracellularCIDA IEA 
protein bindingFIPI IPI IPI IPI IPI IPI ISS ISS IEA 
cyclin-dependent protein kinase regulator activityFIEA IDA ISS IEA 
kinase activityFIDA ISS 
protein kinase bindingFIDA 
protein kinase activityFIEA IDA ISS IEA 
G1/S transition of mitotic cell cyclePNAS ISS 
regulation of progression through cell cyclePIDA IDA TAS ISS TAS 
fat cell differentiationPIEA IDA ISS IEA 
protein amino acid phosphorylationPIEA IDA IDA ISS IEA 
cell cyclePIEA IDA IEA 
unfolded protein responsePIEA IDA IEA 
response to calcium ionPIEP 
cell divisionPIEA IEA IEA 
response to iron ionPIEP 
re-entry into mitotic cell cyclePIEA IDA ISS IEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (23)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
cellular phenotypeMPUn
craniofacial phenotypeMPUn
growth/size phenotypeMPUn Un Un Un
endocrine/exocrine gland phenotypeMPUn Un
homeostasis/metabolism phenotypeMPUn
behavior/neurological phenotypeMPUn Un Un Un
life span-post-weaning/agingMPUn
immune system phenotypeMPUn
lethality-embryonic/perinatalMPUn Un
skeleton phenotypeMPUn
lethality-postnatalMPUn Un
cardiovascular system phenotypeMPUn
reproductive system phenotypeMPUn Un Un Un
hematopoietic system phenotypeMPUn
respiratory system phenotypeMPUn
vision/eye phenotypeMPUn Un Un Un
nervous system phenotypeMPUn Un
tumorigenesisNUn Un Un ISS
increased cell proliferationNIED
Increased Cell SizeNIED
decreased body sizeNISS
cardiac hypertrophyNIED
abnormal liver regenerationNIED

Disease (2)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
CardiomegalyDIED
Multiple MyelomaDISS

Pathway (2)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
S phaseWIEA
G1 phaseWIEA

KEGG Pathway (8)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Glioma (05214)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Chronic myeloid leukemia (05220)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Cell cycle (04110)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Jak-STAT signaling pathway (04630)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Wnt signaling pathway (04310)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Colorectal cancer (05210)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Pancreatic cancer (05212)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Focal adhesion (04510)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway