IpiRecord: IPI00191681

IPI00191681 - Itgb1, INTEGRIN BETA-1 PRECURSOR.
Uniprot Accession: A2RRT8
Uniprot ID: A2RRT8_RAT
Mapping: Chr 19, 58601188 - 58628500
Entrez Gene: 24511
Entrez MapView: Geneprod
RGD: 2927
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_14067)
Rat: Itgb1, INTEGRIN BETA-1 PRECURSOR.
Mouse: Itgb1, INTEGRIN BETA-1 PRECURSOR.
Mouse: Itgb1, PROTEIN, FULL INSERT SEQUENCE (FRAGMENT).
Mouse: Itgb1, INTEGRIN BETA1D (FRAGMENT).
Rat: Itgb1, 9 KDA PROTEIN.
Human: ITGB1, ISOFORM BETA-1C OF INTEGRIN BETA-1 PRECURSOR.
Human: ITGB1, ISOFORM BETA-1C-2 OF INTEGRIN BETA-1 PRECURSOR.
Human: ITGB1, ISOFORM BETA-1A OF INTEGRIN BETA-1 PRECURSOR.
Human: ITGB1, ISOFORM BETA-1B OF INTEGRIN BETA-1 PRECURSOR.
Human: ITGB1, ISOFORM BETA-1D OF INTEGRIN BETA-1 PRECURSOR.
Human: ITGB1, INTEGRIN, BETA 1.
Human: ITGB1, INTEGRIN BETA 1 ISOFORM 1A PRECURSOR.
Human: ITGB1, INTEGRIN, BETA 1.

Annotations for Itgb1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
plasma membraneCIDA IDA IDA ISS 
integrin complexCIEA IEA ISS IMP IDA IEA IC 
extracellular spaceCISS 
synaptosomeCIDA ISS 
focal adhesionCIDA 
lipid raftCIDA 
integral to membraneCIEA IEA ISS IEA 
sarcolemmaCIDA ISS 
membraneCIEA IEA 
acrosomeCIDA 
neuromuscular junctionCIDA ISS 
basement membraneCIDA 
endoplasmic reticulumCIDA 
membrane fractionCIDA IDA 
cytoplasmCISS 
integrin bindingFIPI ISS IMP 
peptide bindingFIDA 
protein heterodimerization activityFIC IMP 
cell adhesion molecule bindingFISS 
bindingFIEA IEA 
protein bindingFIEA IPI IPI IPI ISS IPI ISS 
receptor activityFIEA IEA IEA IEA IEA 
in utero embryonic developmentPIMP 
positive regulation of MAPKKK cascadePIDA 
cardioblast cell fate specificationPIMP 
regulation of progression through cell cyclePIMP ISS 
integrin-mediated signaling pathwayPIEA IEA IEA IEA ISS IDA IEA 
cell adhesionPIEA IEA IEA ISS IDA IEA 
G1/S transition of mitotic cell cyclePIMP ISS 
cellular calcium ion homeostasisPIDA 
regulation of G-protein coupled receptor protein signaling pathwayPIMP 
cell-matrix adhesionPIEA IEA IEA 
sarcomere organizationPIMP 
negative regulation of cell differentiationPIMP ISS 
positive regulation of cell proliferationPIMP ISS 
tissue homeostasisPIMP 
multicellular organismal developmentPIEA IEA ISS IEA 
cardioblast differentiationPIMP 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (24)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
cellular phenotypeMPUn Un Un
craniofacial phenotypeMPUn Un
skin/coat/nails phenotypeMPUn Un
behavior/neurological phenotypeMPUn Un Un Un
endocrine/exocrine gland phenotypeMPUn Un Un
homeostasis/metabolism phenotypeMPUn Un Un
other phenotypeMPUn
embryogenesis phenotypeMPUn Un Un
lethality-embryonic/perinatalMPUn Un Un Un Un Un
skeleton phenotypeMPUn
muscle phenotypeMPUn Un Un Un
lethality-postnatalMPUn
nervous system phenotypeMPUn Un Un Un Un
respiratory system phenotypeMPUn
tumorigenesisMPUn Un Un
vision/eye phenotypeMPUn Un Un Un
limbs/digits/tail phenotypeMPUn
cardiovascular system phenotypeMPUn Un Un
digestive/alimentary phenotypeMPUn Un Un
hematopoietic system phenotypeMPUn Un
reproductive system phenotypeMPUn
liver/biliary system phenotypeMPUn
life span-post-weaning/agingMPUn Un Un Un
growth/size phenotypeMPUn Un Un Un Un

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (4)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
integrin signaling pathwayWISSIDA
hypertrophic cardimyopathyWISS
glomerulonephritisWTAS
altered integrin signaling pathwayWISS

KEGG Pathway (6)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
ECM-receptor interaction (04512)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Cell adhesion molecules (CAMs) (04514)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Pathogenic Escherichia coli infection - EHEC (05130)Present in KEGG pathway Not present in KEGG pathwayNot present in KEGG pathway
Pathogenic Escherichia coli infection - EPEC (05131)Present in KEGG pathway Not present in KEGG pathwayNot present in KEGG pathway
Leukocyte transendothelial migration (04670)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Regulation of actin cytoskeleton (04810)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Axon guidance (04360)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Focal adhesion (04510)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway