IpiRecord: IPI00192309

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
axon	C			IDA
plasma membrane	C	IDA	ISS	ISS IMP IDA
sarcolemma	C			IDA
intracellular part	C			IDA
apical plasma membrane	C	IEA	IDA	ISS IEA
integral to plasma membrane	C	TAS	IEA	ISS
lysosome	C	TAS		ISS
membrane	C		IEA
dendrite	C			IDA
receptor complex	C	IDA		ISS ISS IEA
integral to membrane	C		RCA	IEA ISS
nucleus	C	IEA	IDA	ISS IEA
caveola	C			TAS IDA
endosome	C	TAS		ISS IDA
membrane fraction	C	IEA	IDA IDA	IDA ISS IDA
protein binding	F	IPI	IPI	ISS
beta2-adrenergic receptor activity	F	IDA	RCA IDA IDA IDA IDA IDA IDA	ISS IDA ISS ISS IEA
adrenoceptor activity	F		RCA	IEA ISS
receptor activity	F	IEA	IEA	IEA
G-protein coupled receptor activity	F		IEA
protein complex binding	F			IPI
protein homodimerization activity	F	IDA		ISS ISS IEA
norepinephrine binding	F	IDA		ISS ISS IEA
rhodopsin-like receptor activity	F	IEA	IEA	IEA
epinephrine binding	F			TAS
PDZ domain binding	F			TAS
drug binding	F			IDA
signal transducer activity	F		IEA
adenylate cyclase activation	P	IDA		ISS ISS IEA
norepinephrine-epinephrine vasodilation during regulation of blood pressure	P	IEA	IMP IGI IGI	ISS IEA
negative regulation of smooth muscle contraction	P	IEA	IGI	ISS IEA
negative regulation of body size	P	IEA	IGI	ISS IEA
activation of MAPK activity	P	TAS		ISS
positive regulation of vasodilation	P			IDA
negative regulation of ossification	P			IMP
G-protein coupled receptor protein signaling pathway	P	TAS	RCA IEA	IEA IDA ISS ISS
norepinephrine-epinephrine regulation of blood pressure	P		IMP	ISS
positive regulation of MAPKKK cascade	P	IDA		ISS ISS IEA
negative regulation of inflammatory response	P			IDA
regulation of sodium ion transport	P	IEA	IMP	ISS IEA
receptor-mediated endocytosis	P	IDA		ISS ISS IEA
transmembrane receptor protein tyrosine kinase activation (dimerization)	P	TAS		ISS
protein kinase cascade	P	TAS		ISS
heat generation	P	IEA	IGI	ISS IEA
positive regulation of apoptosis	P			IMP
G-protein signaling, coupled to cAMP nucleotide second messenger	P			ISS
G-protein signaling, adenylate cyclase activating pathway	P		IDA IMP IDA	ISS
positive regulation of heart contraction	P			IDA
positive regulation of skeletal muscle growth	P			IMP
brown fat cell differentiation	P	IEA	IGI	ISS IEA
regulation of sensory perception of pain	P			IMP
positive regulation of cell proliferation	P			IDA
endosome to lysosome transport	P	TAS		ISS
negative regulation of calcium ion transport via voltage gated calcium channel	P			IDA
signal transduction	P		IEA	IEA
bone resorption	P	IEA	IMP	ISS IEA
diet induced thermogenesis	P	IEA	IGI	ISS IEA
positive regulation of bone mineralization	P	IEA	IMP	ISS IEA
response to cold	P	IEA	IGI IGI	ISS IEA
positive regulation of transcription from RNA polymerase II promoter	P	IEA	IGI	ISS IEA
arrestin mediated desensitization of G-protein coupled receptor protein signaling pathway	P	IDA		ISS ISS IEA

Cellular Component

Biological Process

Molecular Function

Phenotype (12)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
congestive heart failure	D			IED
skeleton phenotype	MP		Un
behavior/neurological phenotype	MP		Un
endocrine/exocrine gland phenotype	MP		Un
homeostasis/metabolism phenotype	MP		Un
immune system phenotype	MP		Un
adipose tissue phenotype	MP		Un
hematopoietic system phenotype	MP		Un
growth/size phenotype	MP		Un
cardiovascular system phenotype	MP		Un
muscle phenotype	MP		Un
obese	N			ISS

Disease (14)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Hypertrophy, Left Ventricular	D			ISS
Obesity	D			ISSISS
Sepsis	D			IED
Metabolic Diseases	D			ISS
Metabolic Syndrome X	D			ISS
Diabetes Mellitus, Non-Insulin-Dependent	D			ISS
Myocardial Infarction	D			ISS
Insulin Resistance	D			IEDISS
Fatty Liver	D			ISS
Myocardial Reperfusion Injury	D			IED
Coronary Disease	D			ISS
Reperfusion Injury	D			IED
Hypercholesterolemia, Familial	D			ISS
Hypertension	D			ISSISS

Pathway (2)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
G protein signaling pathway via Galphai family	W			IMP
G protein signaling pathway via Galphas family	W			TAS

KEGG Pathway (2)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Neuroactive ligand-receptor interaction (04080)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Calcium signaling pathway (04020)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway