IpiRecord: IPI00192438

IPI00192438 - Il1a, 24 PROIL-1 ALPHA.
Uniprot Accession: Q9ESW2
Uniprot ID: Q9ESW2_RAT
Mapping: Chr 3, 116913612 - 116923352
Entrez Gene: 24493
Entrez MapView: Geneprod
RGD: 2890
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_3811)
Rat: Il1a, 24 PROIL-1 ALPHA.
Mouse: Il1a, INTERLEUKIN-1 ALPHA PRECURSOR.
Rat: Il1a, INTERLEUKIN-1 ALPHA PRECURSOR.
Rat: Il1a, 31 KDA PROTEIN.
Human: IL1A, INTERLEUKIN-1 ALPHA PRECURSOR.

Annotations for Il1a and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
cytoplasmCNR ISS 
extracellular spaceCTAS IEA IEA ISS 
extracellular regionCIEA IEA IEA IDA 
cytokine activityFIEA 
growth factor activityFIEA 
signal transducer activityFTAS TAS ISS 
interleukin-1, Type I receptor bindingFNAS 
interleukin-1 receptor bindingFIEA IEA 
regulation of progression through cell cyclePIEA IEA IEA 
negative regulation of cell proliferationPTAS ISS 
inflammatory responsePTAS IEA IEA IEA NAS 
cell proliferationPTAS IEA IEA ISS 
cell-cell signalingPNR ISS 
apoptosisPTAS ISS 
immune responsePIEA IEA IEA 
chemotaxisPNR ISS 
feverPIEA IEA IEA 
anti-apoptosisPTAS ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (2)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
immune system phenotypeMPUn
growth/size phenotypeMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (3)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
programmed cell death pathwayWIEA
Alzheimer disease pathwayWIEA
mitogen activated protein kinase signaling pathwayWIEA

KEGG Pathway (5)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Apoptosis (04210)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
MAPK signaling pathway (04010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Hematopoietic cell lineage (04640)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Type I diabetes mellitus (04940)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Cytokine-cytokine receptor interaction (04060)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway