| IPI00192532 - Plcg1, 1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA-1. | |
|---|---|
| Uniprot Accession: P10686 | |
| Uniprot ID: PLCG1_RAT | |
| Mapping: Chr 3, 151522949 - 151565985 | |
| Entrez Gene: 25738 | |
| Entrez MapView: |
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| RGD: 3347 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_4096) |
|---|
| Rat: Plcg1, 1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA-1. |
| Mouse: Plcg1, 1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA-1. |
| Mouse: Plcg1, SEQUENCE (FRAGMENT). |
| Mouse: Plcg1, ELP. |
| Mouse: Plcg1, PHOSPHOLIPASE C, GAMMA 1. |
| Mouse: Plcg1, PHOSPHOLIPASE C, GAMMA 1. |
| Rat: Plcg1, 148 KDA PROTEIN. |
| Human: PLCG1, 1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA-1. |
| Human: PLCG1, PHOSPHOLIPASE C GAMMA 1 ISOFORM A. |
| Human: PLCG1, PLCG1 VARIANT PROTEIN (FRAGMENT). |
| Human: PLCG1, PUTATIVE UNCHARACTERIZED PROTEIN DKFZP434N101 (FRAGMENT). |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cellular_component | C | ND | ||
| neuron projection | C | IDA | ||
| cytoplasm | C | IDA | ISS | TAS |
| hydrolase activity | F | IEA | IEA | IEA |
| protein binding | F | IPI IPI | IPI IPI | IPI ISS ISS IPI IPI IPI IDA |
| phospholipase C activity | F | IEA | ISS | |
| calcium ion binding | F | IEA | IEA IEA | IEA |
| signal transducer activity | F | IEA | IEA | |
| receptor signaling protein activity | F | NAS | ISS | |
| phosphoprotein binding | F | IPI | ||
| insulin receptor binding | F | IDA | ||
| phosphoinositide phospholipase C activity | F | NAS IEA | IEA IEA | ISS IEA |
| lipid metabolic process | P | IEA | IEA | |
| intracellular signaling cascade | P | IEA | IEA | IEA |
| vesicle-mediated transport | P | IPI | ||
| calcium ion transport | P | IMP | ||
| lipid catabolic process | P | IEA | IEA | IEA |
| in utero embryonic development | P | IMP | ISS IEA | |
| signal transduction | P | IEA IEA | TAS |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| growth/size phenotype | MP | Un | ||
| embryogenesis phenotype | MP | Un Un | ||
| lethality-embryonic/perinatal | MP | Un Un | ||
| hematopoietic system phenotype | MP | Un Un | ||
| cardiovascular system phenotype | MP | Un | ||
| abnormal vasculogenesis | N | ISS | ||
| embryonic growth arrest | N | ISS | ||
| abnormal erythropoiesis | N | ISS |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Polycystic Kidney Diseases | D | TAS |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Wnt signaling pathway | W | IEA | ||
| inositol phosphate metabolic pathway | W | IEA | ||
| phosphatidylinositol 3 kinase-Akt signaling pathway | W | IEA |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Glioma (05214) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| T cell receptor signaling pathway (04660) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Epithelial cell signaling in Helicobacter pylori infection (05120) | Present in KEGG pathway | Not present in KEGG pathway | Not present in KEGG pathway |
| Cholera - Infection (05110) | Present in KEGG pathway | Not present in KEGG pathway | Not present in KEGG pathway |
| Fc epsilon RI signaling pathway (04664) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| VEGF signaling pathway (04370) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Leukocyte transendothelial migration (04670) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Calcium signaling pathway (04020) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Inositol phosphate metabolism (00562) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Natural killer cell mediated cytotoxicity (04650) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Phosphatidylinositol signaling system (04070) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |