IpiRecord: IPI00192939

IPI00192939 - Hgf, HEPATOCYTE GROWTH FACTOR PRECURSOR.
Uniprot Accession: P17945
Uniprot ID: HGF_RAT
Mapping: Chr 4, 14864357 - 14932513
Entrez Gene: 24446
Entrez MapView: Geneprod
RGD: 2794
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_4308)
Rat: Hgf, HEPATOCYTE GROWTH FACTOR PRECURSOR.
Mouse: Hgf, ISOFORM LONG OF HEPATOCYTE GROWTH FACTOR PRECURSOR.
Mouse: Hgf, ISOFORM SHORT OF HEPATOCYTE GROWTH FACTOR PRECURSOR.
Human: HGF, ISOFORM 1 OF HEPATOCYTE GROWTH FACTOR PRECURSOR.
Human: HGF, ISOFORM 2 OF HEPATOCYTE GROWTH FACTOR PRECURSOR.
Human: HGF, ISOFORM 3 OF HEPATOCYTE GROWTH FACTOR PRECURSOR.
Human: HGF, ISOFORM 4 OF HEPATOCYTE GROWTH FACTOR PRECURSOR.
Human: HGF, ISOFORM 5 OF HEPATOCYTE GROWTH FACTOR PRECURSOR.
Human: HGF, ISOFORM 6 OF HEPATOCYTE GROWTH FACTOR PRECURSOR.
Human: HGF, HEPATOCYTE GROWTH FACTOR ISOFORM 1 PREPROPROTEIN VARIANT (FRAGMENT).

Annotations for Hgf and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
serine-type endopeptidase activityFIEA IEA IEA 
hepatocyte growth factor receptor bindingFTAS 
growth factor activityFIEA IEA ISS 
calcium ion bindingFIEA 
protein bindingFISS 
cell motilityPTAS 
hepatocyte growth factor receptor signaling pathwayPIDA IEA ISS 
myoblast proliferationPIDA IEA ISS 
positive regulation of cell proliferationPTAS 
activation of MAPK activityPIDA IEA ISS 
mitosisPISS 
cell proliferationPIDA IDA TAS ISS 
liver developmentPIDA 
cell morphogenesisPIDA IEA ISS 
proteolysisPIEA IEA IEA 
anti-apoptosisPIDA IEA ISS 
blood coagulationPIEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (9)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
embryogenesis phenotypeMPUn Un
lethality-embryonic/perinatalMPUn Un
growth/size phenotypeMPUn Un
hematopoietic system phenotypeMPUn
cardiovascular system phenotypeMPUn
liver/biliary system phenotypeMPUn Un Un
embryonic lethalityNIEA
small liverNIEA
abnormal placental developmentNIEA

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
HypertensionDISS

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (2)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Cytokine-cytokine receptor interaction (04060)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Focal adhesion (04510)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway